ENSMUSG00000015001


Mus musculus

Features
Gene ID: ENSMUSG00000015001
  
Biological name :Oc90
  
Synonyms : Mus musculus otoconin 90 (Oc90), transcript variant 2, mRNA. / Oc90 / Q9Z0L3
  
Possible biological names infered from orthology : AC100868.1 / otoconin 90 / Q02509
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: D1
Gene start: 65876053
Gene end: 65912397
  
Corresponding Affymetrix probe sets: 10429048 (MoGene1.0st)   1452403_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062865
Ensembl peptide - ENSMUSP00000078709
Ensembl peptide - ENSMUSP00000114254
Ensembl peptide - ENSMUSP00000121227
NCBI entrez gene - 18256     See in Manteia.
MGI - MGI:1313269
RefSeq - XM_011245492
RefSeq - NM_001347038
RefSeq - NM_010953
RefSeq - XM_011245488
RefSeq - XM_011245489
RefSeq - XM_011245490
RefSeq - XM_011245491
RefSeq Peptide - NP_001333967
RefSeq Peptide - NP_035083
swissprot - F6ZCJ0
swissprot - Q9Z0L3
swissprot - F6T2M1
swissprot - Q80ZM2
Ensembl - ENSMUSG00000015001
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oc90ENSDARG00000001721Danio rerio
 ENSGALG00000030128Gallus gallus
 AC100868.1ENSG00000258417Homo sapiens
 OC90ENSG00000253117Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9QXX3 / Pla2g10 / phospholipase A2, group X / O15496*ENSMUSG000000226839
Q9QZT4 / Pla2g2f / Group IIF secretory phospholipase A2 / Q9BZM2* / phospholipase A2 group IIF*ENSMUSG000000287499
Q9Z0Y2 / Pla2g1b / Phospholipase A2 / P04054* / phospholipase A2 group IB*ENSMUSG000000295228
Pla2g5 / phospholipase A2, group V / P39877*ENSMUSG000000411938
Q9WVF6 / Pla2g2d / phospholipase A2, group IID / Q9UNK4*ENSMUSG000000412028
Pla2g2a / Mus musculus phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), transcript variant 1, coding, mRNA. / P14555* / phospholipase A2 group IIA*ENSMUSG000000589088
Q9QUL3 / Pla2g2e / Group IIE secretory phospholipase A2 / Q9NZK7* / phospholipase A2 group IIE*ENSMUSG000000287517


Protein motifs (from Interpro)
Interpro ID Name
 IPR001211  Phospholipase A2
 IPR016090  Phospholipase A2 domain
 IPR033112  Phospholipase A2, aspartic acid active site
 IPR033113  Phospholipase A2, histidine active site
 IPR036444  Phospholipase A2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0050482 arachidonic acid secretion IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004623 phospholipase A2 activity IEA
 molecular_functionGO:0005198 structural molecule activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dlx2tm1Jlr/Dlx2tm1Jlr
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Oc90df1H5R/Oc90+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002894 abnormal otoliths "malformed crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

 MP:0003143 enlarged otoliths "increased average size of the crystalline calciferous particles adhering to the otolithic membrane" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

 MP:0003144 reduced number of otoliths "decreased average number of the crystalline calciferous particles adhering to the otolithic membrane" [J:30611, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

 MP:0003149 abnormal tectorial membrane morphology "malformation, malfunction or absence of the overlaying membrane of cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells; sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair cell membrane potential, transducing sound into electrical signals" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:77634]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

 MP:0006089 abnormal saccule morphology "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

 MP:0006090 abnormal utricle morphology "malformation in the larger of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940]
Show

Allelic Composition: Mesp2tm5(Notch1)Ysa/Mesp2tm5(Notch1)Ysa,Psen1tm1Shs/Psen1tm1Shs
Genetic Background: involves: C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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