ENSMUSG00000021933


Mus musculus

Features
Gene ID: ENSMUSG00000021933
  
Biological name :Gucy1b2
  
Synonyms : Gucy1b2
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D1
Gene start: 62392676
Gene end: 62456289
  
Corresponding Affymetrix probe sets: 10420675 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000022501
Ensembl peptide - ENSMUSP00000128114
NCBI entrez gene - 239134     See in Manteia.
MGI - MGI:2660873
RefSeq - XM_011245061
RefSeq - NM_001204340
RefSeq - NM_172810
RefSeq - XM_006518985
RefSeq - XM_006518987
RefSeq - XM_006518988
RefSeq Peptide - NP_001191269
RefSeq Peptide - NP_766398
swissprot - E9Q6H0
swissprot - Q8BXH3
Ensembl - ENSMUSG00000021933
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gucy1b2ENSDARG00000056591Danio rerio
 ENSGALG00000005076Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gucy2dENSMUSG0000007400322
Gucy2e / P52785 / Guanylyl cyclase GC-E / GUCY2D* / Q02846* / guanylate cyclase 2D, retinal*ENSMUSG0000002089021
Npr1 / P18293 / natriuretic peptide receptor 1 / P16066*ENSMUSG0000002793121
O54865 / Gucy1b1 / guanylate cyclase 1, soluble, beta 1 / Q02153* / guanylate cyclase 1 soluble subunit beta 1*ENSMUSG0000002800521
Gucy1a2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSMUSG0000004162421
Gucy2f / Q5SDA5 / Retinal guanylyl cyclase 2 / P51841* / guanylate cyclase 2F, retinal*ENSMUSG0000004228221
Npr2 / Q6VVW5 / natriuretic peptide receptor 2 / P20594*ENSMUSG0000002846920
Q9ERL9 / Gucy1a1 / guanylate cyclase 1, soluble, alpha 1 / Q02108* / guanylate cyclase 1 soluble subunit alpha 1*ENSMUSG0000003391020
Gucy2g / Q6TL19 / Guanylate cyclase 2G ENSMUSG0000005552320
Gucy2c / Q3UWA6 / Heat-stable enterotoxin receptor / P25092* / guanylate cyclase 2C*ENSMUSG0000004263819


Protein motifs (from Interpro)
Interpro ID Name
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR011644  Heme NO-binding
 IPR011645  Haem NO binding associated
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR024096  NO signalling/Golgi transport ligand-binding domain superfamily
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001764 abnormal homeostasis "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Stk39tm2.1Arte/Stk39tm2.1Arte
Genetic Background: involves: C57BL/6J

 MP:0002067 abnormal sensory capabilities/reflexes/nociception "inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Stk39tm2.1Arte/Stk39tm2.1Arte
Genetic Background: involves: C57BL/6J

Allelic Composition: Gucy1b2tm3Mom/Gucy1b2tm3Mom,Trpc2tm1Mom/Trpc2tm1Mom
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011677 abnormal olfactory sensory neuron physiology "any functional anomaly of cells that innervate the olfactory epithelium and are responsible for receiving and transmitting odorant signals" [MGI:csmith]
Show

Allelic Composition: Stk39tm2.1Arte/Stk39tm2.1Arte
Genetic Background: involves: C57BL/6J

Allelic Composition: Gucy1b2tm3Mom/Gucy1b2tm3Mom,Trpc2tm1Mom/Trpc2tm1Mom
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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