ENSMUSG00000022324


Mus musculus

Features
Gene ID: ENSMUSG00000022324
  
Biological name :Matn2
  
Synonyms : Matn2 / Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA. / O08746
  
Possible biological names infered from orthology : matrilin 2 / O00339
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B3.1
Gene start: 34306677
Gene end: 34436273
  
Corresponding Affymetrix probe sets: 10423599 (MoGene1.0st)   1419442_at (Mouse Genome 430 2.0 Array)   1455978_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154740
Ensembl peptide - ENSMUSP00000022947
Ensembl peptide - ENSMUSP00000128202
Ensembl peptide - ENSMUSP00000154040
Ensembl peptide - ENSMUSP00000154572
NCBI entrez gene - 17181     See in Manteia.
MGI - MGI:109613
RefSeq - XM_006520023
RefSeq - NM_001358780
RefSeq - NM_016762
RefSeq Peptide - NP_001345709
RefSeq Peptide - NP_058042
swissprot - O08746
swissprot - A0A0A0MQM7
Ensembl - ENSMUSG00000022324
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MATN2ENSGALG00000044675Gallus gallus
 MATN2ENSG00000132561Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Matn4 / matrilin 4 / O95460*ENSMUSG0000001699534
Matn1 / P51942 / Cartilage matrix protein / P21941* / matrilin 1, cartilage matrix protein*ENSMUSG0000004053326
Matn3 / O35701 / Matrilin-3 / O15232*ENSMUSG0000002058319
Q6NZL8 / Scube1 / signal peptide, CUB domain, EGF-like 1 / Q8IWY4* / signal peptide, CUB domain and EGF like domain containing 1*ENSMUSG0000001676315
Q66PY1 / Scube3 / Signal peptide, CUB and EGF-like domain-containing protein 3 / Q8IX30* / signal peptide, CUB domain and EGF like domain containing 3*ENSMUSG0000003867715
Q9JJS0 / Scube2 / Signal peptide, CUB and EGF-like domain-containing protein 2 / Q9NQ36* / signal peptide, CUB domain and EGF like domain containing 2*ENSMUSG0000000727913
Cd93 / O89103 / Complement component C1q receptor / Q9NPY3* / CD93 molecule*ENSMUSG0000002743511
Vwa1 / Q8R2Z5 / von Willebrand factor A domain containing 1 / Q6PCB0*ENSMUSG0000004211610
Thbd / P15306 / thrombomodulin / P07204*ENSMUSG0000007474310
Cd248 / Q91V98 / Endosialin / Q9HCU0* / CD248 molecule*ENSMUSG000000564819
Q8VCP9 / Clec14a / C-type lectin domain family 14 member A / Q86T13* / C-type lectin domain containing 14A*ENSMUSG000000459305


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002035  von Willebrand factor, type A
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR019466  Matrilin, coiled-coil trimerisation domain
 IPR030747  Matrilin-2
 IPR036337  Matrilin, coiled-coil domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IDA
 biological_processGO:0007411 axon guidance IGI
 biological_processGO:0008347 glial cell migration IDA
 biological_processGO:0031104 dendrite regeneration IMP
 biological_processGO:0031175 neuron projection development IDA
 biological_processGO:0048678 response to axon injury IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptpn11tm1Bgn/Ptpn11+
Genetic Background: involves: 129S4/SvJae * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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