ENSMUSG00000027435


Mus musculus

Features
Gene ID: ENSMUSG00000027435
  
Biological name :Cd93
  
Synonyms : Cd93 / Complement component C1q receptor / O89103
  
Possible biological names infered from orthology : CD93 molecule / Q9NPY3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: G3
Gene start: 148436640
Gene end: 148443563
  
Corresponding Affymetrix probe sets: 10488382 (MoGene1.0st)   1419589_at (Mouse Genome 430 2.0 Array)   1441907_s_at (Mouse Genome 430 2.0 Array)   1441908_x_at (Mouse Genome 430 2.0 Array)   1449521_at (Mouse Genome 430 2.0 Array)   1456046_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096876
NCBI entrez gene - 17064     See in Manteia.
MGI - MGI:106664
RefSeq - NM_010740
RefSeq Peptide - NP_034870
swissprot - O89103
Ensembl - ENSMUSG00000027435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD93ENSGALG00000008359Gallus gallus
 CD93ENSG00000125810Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Thbd / P15306 / thrombomodulin / P07204*ENSMUSG0000007474324
Cd248 / Q91V98 / Endosialin / Q9HCU0* / CD248 molecule*ENSMUSG0000005648122
Q66PY1 / Scube3 / Signal peptide, CUB and EGF-like domain-containing protein 3 / Q8IX30* / signal peptide, CUB domain and EGF like domain containing 3*ENSMUSG0000003867721
Q6NZL8 / Scube1 / signal peptide, CUB domain, EGF-like 1 / Q8IWY4* / signal peptide, CUB domain and EGF like domain containing 1*ENSMUSG0000001676320
Q9JJS0 / Scube2 / Signal peptide, CUB and EGF-like domain-containing protein 2 / Q9NQ36* / signal peptide, CUB domain and EGF like domain containing 2*ENSMUSG0000000727918
Matn2 / O08746 / Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA. / O00339* / matrilin 2*ENSMUSG0000002232416
Matn4 / matrilin 4 / O95460*ENSMUSG0000001699514
Q8VCP9 / Clec14a / C-type lectin domain family 14 member A / Q86T13* / C-type lectin domain containing 14A*ENSMUSG0000004593014
Matn3 / O35701 / Matrilin-3 / O15232*ENSMUSG0000002058310
Matn1 / P51942 / Cartilage matrix protein / P21941* / matrilin 1, cartilage matrix protein*ENSMUSG000000405339
Vwa1 / Q8R2Z5 / von Willebrand factor A domain containing 1 / Q6PCB0*ENSMUSG000000421165


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0098609 cell-cell adhesion ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 molecular_functionGO:0001849 complement component C1q binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001798 impaired macrophage phagocytosis "reduced ability of these phagocytic cells to internalize particulate matter" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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