ENSMUSG00000025348


Mus musculus

Features
Gene ID: ENSMUSG00000025348
  
Biological name :Itga7
  
Synonyms : Itga7 / Mus musculus integrin alpha 7 (Itga7), transcript variant 2, mRNA.
  
Possible biological names infered from orthology : integrin subunit alpha 7 / Q13683
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 128933818
Gene end: 128958282
  
Corresponding Affymetrix probe sets: 10367440 (MoGene1.0st)   1418393_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096712
Ensembl peptide - ENSMUSP00000151760
Ensembl peptide - ENSMUSP00000151960
NCBI entrez gene - 16404     See in Manteia.
MGI - MGI:102700
RefSeq - XM_017313813
RefSeq - NM_001330160
RefSeq - NM_008398
RefSeq - XM_006513267
RefSeq - XM_006513269
RefSeq - XM_006513270
RefSeq Peptide - NP_001317089
RefSeq Peptide - NP_032424
swissprot - G3X9Q1
swissprot - Q3TZS3
swissprot - A0A1W2P7M9
Ensembl - ENSMUSG00000025348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGA7ENSG00000135424Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itga6 / Q61739 / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain / P23229* / integrin subunit alpha 6*ENSMUSG0000002711146
Itga3 / Q62470 / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain / P26006* / integrin subunit alpha 3*ENSMUSG0000000150736
Itgav / P43406 / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain / P06756* / integrin subunit alpha V*ENSMUSG0000002708727
Itga5 / P11688 / Integrin alpha-5 Integrin alpha-5 heavy chain Integrin alpha-5 light chain / P08648* / integrin subunit alpha 5*ENSMUSG0000000055526
Itga8 / A2ARA8 / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain / P53708* / integrin subunit alpha 8*ENSMUSG0000002676826
Itga2b / Q9QUM0 / integrin alpha 2b / P08514* / integrin subunit alpha 2b*ENSMUSG0000003466424
Itga9 / B8JK39 / Integrin alpha-9 / Q13797* / integrin subunit alpha 9*ENSMUSG0000003911524
Itga4 / integrin subunit alpha 4 / P13612*ENSMUSG0000002700923
Itga1 / Q3V3R4 / Integrin alpha-1 / P56199* / integrin subunit alpha 1*ENSMUSG0000004228421
Itga10 / integrin subunit alpha 10 / O75578*ENSMUSG0000009021021
Itgax / Q9QXH4 / Integrin alpha-X / P20702* / integrin subunit alpha X*ENSMUSG0000003078920
Itga11 / integrin subunit alpha 11 / Q9UKX5*ENSMUSG0000003224320
Itga2 / Q62469 / Integrin alpha-2 / P17301* / integrin subunit alpha 2*ENSMUSG0000001553319
Itgad / Q3V0T4 / Integrin alpha-D / Q13349* / integrin subunit alpha D*ENSMUSG0000007036919
Itgae / Q60677 / integrin alpha E, epithelial-associated / P38570* / integrin subunit alpha E*ENSMUSG0000000594718
Itgam / integrin alpha M / P11215* / integrin subunit alpha M*ENSMUSG0000003078618
Itgal / P24063 / Integrin alpha-L / P20701* / integrin subunit alpha L*ENSMUSG0000003083018
Itgam / P11215* / integrin subunit alpha M*ENSMUSG0000010859618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0034113 heterotypic cell-cell adhesion IEA
 biological_processGO:0035987 endodermal cell differentiation IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Laminin interactions
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000069 kyphoscoliosis "kyphosis combined with scoliosis" [MGI:CML, J:66943]
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Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000752 dystrophic muscle "progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001388 abnormal stationary movement "altered ability or inability to change body posture or shift a body part" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001442 decreased grooming behavior "reduced amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: a/a,Tyrp1b/Tyrp1b
Genetic Background: Not Specified

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: a/a,Tyrp1b/Tyrp1b
Genetic Background: Not Specified

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002279 abnormal diaphragm morphology "structural defect in the thin musculomebraneous barrier that separates the abdominal and thoracic cavities; these muscles often used for breathing control" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002651 abnormal sciatic nerve "malformation, absence or misprojection of the nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

 MP:0002975 vascular smooth muscle hypertrophy "increase in size or thickness of the smooth muscle of the vascular wall" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0003081 abnormal soleus morphology "anomaly in the the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0003852 skeletal muscle necrosis "pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004121 abnormal sarcolemma morphology "structural anomaly in the plasma membrane of a muscle fiber that is cabable of conducting electrical impuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005405 axon degeneration "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

 MP:0005489 vascular smooth muscle cell hyperplasia "increased numbers of smooth muscle cells in the vascular wall" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:48446]
Show

Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0005592 abnormal vascular smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009399 increased skeletal muscle fiber size "increase in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009403 increased variability of skeletal muscle fiber size "greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009409 abnormal skeletal muscle fiber type ratio "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009413 skeletal muscle fiber atrophy "a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0009417 skeletal muscle atrophy "a wasting of skeletal muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009419 skeletal muscle fibrosis "formation of fibrous tissue within skeletal muscle as a result of repair or a reactive process" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0010050 hypermyelination "anomaly in the process by which myelin sheaths are formed and maintained around neurons resulting in increased myelin formation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

 MP:0010090 increased circulating creatine kinase level "an elevation in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0010225 abnormal quadriceps morphology "any structural anomaly of the group of four muscles (rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis) which extend down the front of the thigh and are the major extensors of the knee joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0010227 decreased quadriceps weight "reduction in the weight of the group of four muscles (rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis) which extend down the front of the thigh and are the major extensors of the knee joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk,Sspntm1Kcam/Sspntm1Kcam
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011083 complete lethality at weaning "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]
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Allelic Composition: Itga7tm1Umr/Itga7tm1Umr,Sgcgtm1Mcn/Sgcgtm1Mcn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Gdnftm1Rosl/Gdnf+
Genetic Background: involves: 129S2/SvPas

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0011904 abnormal Schwann cell physiology "any functional anomaly of the cells which form the insulating myelin sheaths of peripheral axons" [MESH:A08.637.800]
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Allelic Composition: Ptpn1tm1Bbk/Ptpn1tm1Bbk
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

 MP:0020452 abnormal axon radial sorting "any anomaly in the process by which immature Schwann cells surround axons of mixed caliber and send cytoplasmic processes that resemble lamellipodia between axons, to progressively choose and segregate the larger axons at the periphery of the bundle" [MGI:smb, PMID:25686621]
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Allelic Composition: Itga6tm2Egl/Itga6tm2Egl,Itga7tm1Umr/Itga7tm1Umr,Tg(Mpz-cre)26Mes/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025809 Itgb1 / P09055 / Integrin beta-1 / P05556* / integrin subunit beta 1*  / complex






 

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