ENSMUSG00000090210


Mus musculus

Features
Gene ID: ENSMUSG00000090210
  
Biological name :Itga10
  
Synonyms : integrin subunit alpha 10 / Itga10
  
Possible biological names infered from orthology : O75578
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.1
Gene start: 96645584
Gene end: 96664519
  
Corresponding Affymetrix probe sets: 10494467 (MoGene1.0st)   1440235_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029744
Ensembl peptide - ENSMUSP00000112393
NCBI entrez gene - 213119     See in Manteia.
MGI - MGI:2153482
RefSeq - NM_001302471
RefSeq Peptide - NP_001289400
swissprot - E9Q6R1
swissprot - E9PXZ3
Ensembl - ENSMUSG00000090210
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga10ENSDARG00000002507Danio rerio
 ITGA10ENSG00000143127Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itga11 / integrin subunit alpha 11 / Q9UKX5*ENSMUSG0000003224343
Itga1 / Q3V3R4 / Integrin alpha-1 / P56199* / integrin subunit alpha 1*ENSMUSG0000004228436
Itga2 / Q62469 / Integrin alpha-2 / P17301* / integrin subunit alpha 2*ENSMUSG0000001553333
Itgax / Q9QXH4 / Integrin alpha-X / P20702* / integrin subunit alpha X*ENSMUSG0000003078927
Itgal / P24063 / Integrin alpha-L / P20701* / integrin subunit alpha L*ENSMUSG0000003083027
Itgam / integrin alpha M / P11215* / integrin subunit alpha M*ENSMUSG0000003078626
Itgad / Q3V0T4 / Integrin alpha-D / Q13349* / integrin subunit alpha D*ENSMUSG0000007036926
Itgam / P11215* / integrin subunit alpha M*ENSMUSG0000010859626
Itgae / Q60677 / integrin alpha E, epithelial-associated / P38570* / integrin subunit alpha E*ENSMUSG0000000594724
Itga7 / Mus musculus integrin alpha 7 (Itga7), transcript variant 2, mRNA. / Q13683* / integrin subunit alpha 7*ENSMUSG0000002534821
Itga3 / Q62470 / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain / P26006* / integrin subunit alpha 3*ENSMUSG0000000150720
Itga6 / Q61739 / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain / P23229* / integrin subunit alpha 6*ENSMUSG0000002711120
Itga5 / P11688 / Integrin alpha-5 Integrin alpha-5 heavy chain Integrin alpha-5 light chain / P08648* / integrin subunit alpha 5*ENSMUSG0000000055519
Itga4 / integrin subunit alpha 4 / P13612*ENSMUSG0000002700919
Itga9 / B8JK39 / Integrin alpha-9 / Q13797* / integrin subunit alpha 9*ENSMUSG0000003911519
Itga8 / A2ARA8 / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain / P53708* / integrin subunit alpha 8*ENSMUSG0000002676818
Itgav / P43406 / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain / P06756* / integrin subunit alpha V*ENSMUSG0000002708718
Itga2b / Q9QUM0 / integrin alpha 2b / P08514* / integrin subunit alpha 2b*ENSMUSG0000003466418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion ISO
 biological_processGO:0007229 integrin-mediated signaling pathway ISO
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034680 integrin alpha10-beta1 complex ISO
 molecular_functionGO:0098639 collagen binding involved in cell-matrix adhesion ISO


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000164 abnormal cartilage development "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0003055 abnormal epiphyseal plate morphology "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0003409 decreased width of hypertrophic chondrocyte zone "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025809 Itgb1 / P09055 / Integrin beta-1 / P05556* / integrin subunit beta 1*  / complex






 

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