ENSMUSG00000027855


Mus musculus

Features
Gene ID: ENSMUSG00000027855
  
Biological name :Sycp1
  
Synonyms : Q62209 / Sycp1 / Synaptonemal complex protein 1
  
Possible biological names infered from orthology : Q15431
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 102818499
Gene end: 102936100
  
Corresponding Affymetrix probe sets: 10500754 (MoGene1.0st)   1427291_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143651
Ensembl peptide - ENSMUSP00000029448
Ensembl peptide - ENSMUSP00000143493
NCBI entrez gene - 20957     See in Manteia.
MGI - MGI:105931
RefSeq - NM_011516
RefSeq - XM_006501229
RefSeq Peptide - NP_035646
swissprot - A0A0G2JGA9
swissprot - Q62209
Ensembl - ENSMUSG00000027855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sycp1ENSDARG00000003904Danio rerio
 SYCP1ENSGALG00000002511Gallus gallus
 SYCP1ENSG00000198765Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008827  Synaptonemal complex protein 1
 IPR024835  Synaptonemal complex protein 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000711 meiotic DNA repair synthesis IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0007130 synaptonemal complex assembly IEA
 biological_processGO:0007131 reciprocal meiotic recombination IMP
 biological_processGO:0007283 spermatogenesis IGI
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0035092 sperm chromatin condensation IGI
 biological_processGO:0051026 chiasma assembly IGI
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0051878 lateral element assembly IGI
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0000800 lateral element TAS
 cellular_componentGO:0000801 central element IDA
 cellular_componentGO:0000802 transverse filament IDA
 cellular_componentGO:0001673 male germ cell nucleus IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0001929 abnormal gametogenesis "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0002777 absent ovarian follicles "lack of the sac-like structures in the ovaries that surround the ova" [J:42612, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

Allelic Composition: Sycp1tm1Aps/Sycp1tm1Aps
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pcdh15av-3J/Pcdh15av-3J
Genetic Background: C57BL/6J-Pcdh15av-3J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027855 Sycp1 / Q62209 / Synaptonemal complex protein 1 / Q15431*  / complex






 

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