ENSDARG00000001975


Danio rerio

Features
Gene ID: ENSDARG00000001975
  
Biological name :hsd11b2
  
Synonyms : hsd11b2 / hydroxysteroid (11-beta) dehydrogenase 2
  
Possible biological names infered from orthology : P51661 / P80365
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 35112052
Gene end: 35126374
  
Corresponding Affymetrix probe sets: Dr.12359.1.A1_at (Zebrafish Array)   NM_212720_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000118501
NCBI entrez gene - 334098     See in Manteia.
RefSeq - NM_212720
RefSeq Peptide - NP_997885
swissprot - F1QLP1
ZFIN ID - ZDB-GENE-030131-6030
Ensembl - ENSDARG00000001975
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD11B2ENSGALG00000028326Gallus gallus
 P80365ENSG00000176387Homo sapiens
 P51661ENSMUSG00000031891Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059* / P51658*ENSDARG0000004555329
bdh1 / 3-hydroxybutyrate dehydrogenase, type 1 / Q80XN0* / Q02338* / 3-hydroxybutyrate dehydrogenase 1* / D-beta-hydroxybutyrate dehydrogenase, mitochondrial *ENSDARG0000005938826
rdh1 / retinol dehydrogenase 1ENSDARG0000001788225
zgc:113142ENSDARG0000003896925
rdh5 / retinol dehydrogenase 5 (11-cis/9-cis) / Q92781* / O55240* / retinol dehydrogenase 5* / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA.*ENSDARG0000000830625
dhrs9 / dehydrogenase/reductase (SDR family) member 9 / Q58NB6* / Q9BPW9* / dehydrogenase/reductase 9*ENSDARG0000001926023
hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061* / P51656*ENSDARG0000002746917
rdh8b / retinol dehydrogenase 8b / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000010506016
rdh8a / retinol dehydrogenase 8a / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000002804816
dhrs7b / dehydrogenase/reductase (SDR family) member 7B / Q6IAN0* / Q99J47* / dehydrogenase/reductase 7B*ENSDARG0000007572616
zgc:109982ENSDARG0000009921715
zmp:0000001048ENSDARG0000001621315
dhrs7 / dehydrogenase/reductase (SDR family) member 7 / Gm4756* / Q9CXR1* / Q9Y394* / dehydrogenase/reductase 7*ENSDARG0000000344415
dhrs7ca / dehydrogenase/reductase (SDR family) member 7Ca / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000003945314
kdsr / 3-ketodihydrosphingosine reductase / Q06136* / Q6GV12*ENSDARG0000001202114
A8E5C5 / dhrs7cb / dehydrogenase/reductase (SDR family) member 7Cb / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000007187712


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain
 IPR020904  Short-chain dehydrogenase/reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033555 multicellular organismal response to stress IDA
 biological_processGO:0034650 cortisol metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity ISS
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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