ENSDARG00000019260


Danio rerio

Features
Gene ID: ENSDARG00000019260
  
Biological name :dhrs9
  
Synonyms : dehydrogenase/reductase (SDR family) member 9 / dhrs9
  
Possible biological names infered from orthology : dehydrogenase/reductase 9 / Q58NB6 / Q9BPW9
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 48706038
Gene end: 48736388
  
Corresponding Affymetrix probe sets: Dr.2961.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000027139
swissprot - F1QJC1
ZFIN ID - ZDB-GENE-030131-1249
Ensembl - ENSDARG00000019260
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHRS9ENSGALG00000010873Gallus gallus
 DHRS9ENSG00000073737Homo sapiens
 Dhrs9ENSMUSG00000027068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rdh5 / retinol dehydrogenase 5 (11-cis/9-cis) / Q92781* / O55240* / retinol dehydrogenase 5* / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA.*ENSDARG0000000830651
rdh1 / retinol dehydrogenase 1ENSDARG0000001788250
bdh1 / 3-hydroxybutyrate dehydrogenase, type 1 / Q80XN0* / Q02338* / 3-hydroxybutyrate dehydrogenase 1* / D-beta-hydroxybutyrate dehydrogenase, mitochondrial *ENSDARG0000005938835
zgc:113142ENSDARG0000003896932
hsd11b2 / hydroxysteroid (11-beta) dehydrogenase 2 / P51661* / P80365*ENSDARG0000000197530
hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059* / P51658*ENSDARG0000004555327
rdh8a / retinol dehydrogenase 8a / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000002804819
hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061* / P51656*ENSDARG0000002746919
rdh8b / retinol dehydrogenase 8b / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000010506019
dhrs7b / dehydrogenase/reductase (SDR family) member 7B / Q6IAN0* / Q99J47* / dehydrogenase/reductase 7B*ENSDARG0000007572618
zgc:109982ENSDARG0000009921718
dhrs7 / dehydrogenase/reductase (SDR family) member 7 / Gm4756* / Q9CXR1* / Q9Y394* / dehydrogenase/reductase 7*ENSDARG0000000344418
zmp:0000001048ENSDARG0000001621317
kdsr / 3-ketodihydrosphingosine reductase / Q06136* / Q6GV12*ENSDARG0000001202116
A8E5C5 / dhrs7cb / dehydrogenase/reductase (SDR family) member 7Cb / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000007187716
dhrs7ca / dehydrogenase/reductase (SDR family) member 7Ca / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000003945315


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain
 IPR020904  Short-chain dehydrogenase/reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0035138 pectoral fin morphogenesis IMP
 biological_processGO:0042572 retinol metabolic process IDA
 biological_processGO:0042574 retinal metabolic process IDA
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060047 heart contraction IMP
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart decreased functionality , abnormal
heart decreased contractility , abnormal
Show

 ZFA:0000140 pancreas pancreas molecular quality , abnormal
Show

 ZFA:0000471 atrium atrium decreased size , abnormal
Show

 ZFA:0001076 intestinal bulb intestinal bulb hypoplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin absent , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton absent , abnormal
Show

 ZFA:0001338 intestine intestine molecular quality , abnormal
intestine morphology , abnormal
intestine lacks all parts of type intestinal villus , abnormal
intestine lacks all parts of type columnar/cuboidal epithelial cell , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium aplastic , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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