ENSG00000073737


Homo sapiens

Features
Gene ID: ENSG00000073737
  
Biological name :DHRS9
  
Synonyms : dehydrogenase/reductase 9 / DHRS9 / Q9BPW9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.1
Gene start: 169064789
Gene end: 169096167
  
Corresponding Affymetrix probe sets: 219799_s_at (Human Genome U133 Plus 2.0 Array)   223952_x_at (Human Genome U133 Plus 2.0 Array)   224009_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407167
Ensembl peptide - ENSP00000473337
Ensembl peptide - ENSP00000407747
Ensembl peptide - ENSP00000350154
Ensembl peptide - ENSP00000388066
Ensembl peptide - ENSP00000388564
Ensembl peptide - ENSP00000389241
Ensembl peptide - ENSP00000391214
NCBI entrez gene - 10170     See in Manteia.
OMIM - 612131
RefSeq - XM_011510475
RefSeq - NM_001142270
RefSeq - NM_001142271
RefSeq - NM_001289763
RefSeq - NM_199204
RefSeq Peptide - NP_001135742
RefSeq Peptide - NP_001135743
RefSeq Peptide - NP_001276692
RefSeq Peptide - NP_954674
swissprot - Q9BPW9
swissprot - C9J430
Ensembl - ENSG00000073737
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhrs9ENSDARG00000019260Danio rerio
 DHRS9ENSGALG00000010873Gallus gallus
 Dhrs9ENSMUSG00000027068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDH16 / O75452 / retinol dehydrogenase 16 (all-trans)ENSG0000013954738
O14756 / HSD17B6 / hydroxysteroid 17-beta dehydrogenase 6ENSG0000002542337
Q8NEX9 / SDR9C7 / short chain dehydrogenase/reductase family 9C member 7ENSG0000017042637
RDH5 / Q92781 / retinol dehydrogenase 5ENSG0000013543736
BDH1 / Q02338 / 3-hydroxybutyrate dehydrogenase 1ENSG0000016126727
P80365 / HSD11B2 / hydroxysteroid 11-beta dehydrogenase 2ENSG0000017638726
P37059 / HSD17B2 / hydroxysteroid 17-beta dehydrogenase 2ENSG0000008669625
RDH8 / retinol dehydrogenase 8 (all-trans)ENSG0000008051118
DHRS7 / Q9Y394 / dehydrogenase/reductase 7ENSG0000010061218
P14061 / HSD17B1 / hydroxysteroid 17-beta dehydrogenase 1ENSG0000010878618
DHRS7B / Q6IAN0 / dehydrogenase/reductase 7BENSG0000010901617
A6NNS2 / DHRS7C / dehydrogenase/reductase 7CENSG0000018454416
KDSR / Q06136 / 3-ketodihydrosphingosine reductaseENSG0000011953713


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002138 retinoic acid biosynthetic process IEA
 biological_processGO:0008209 androgen metabolic process IDA
 biological_processGO:0030855 epithelial cell differentiation NAS
 biological_processGO:0042448 progesterone metabolic process IDA
 biological_processGO:0042572 retinol metabolic process NAS
 biological_processGO:0042904 9-cis-retinoic acid biosynthetic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004022 alcohol dehydrogenase (NAD) activity IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016854 racemase and epimerase activity NAS
 molecular_functionGO:0047035 testosterone dehydrogenase (NAD+) activity IDA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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