ENSG00000080511


Homo sapiens

Features
Gene ID: ENSG00000080511
  
Biological name :RDH8
  
Synonyms : RDH8 / retinol dehydrogenase 8 (all-trans)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.2
Gene start: 10013249
Gene end: 10022279
  
Corresponding Affymetrix probe sets: 220683_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465773
Ensembl peptide - ENSP00000466058
NCBI entrez gene - 50700     See in Manteia.
OMIM - 608575
RefSeq - NM_015725
RefSeq Peptide - NP_056540
swissprot - K7ELF7
swissprot - K7EKT5
Ensembl - ENSG00000080511
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rdh8aENSDARG00000028048Danio rerio
 rdh8bENSDARG00000105060Danio rerio
 Rdh8ENSMUSG00000053773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P14061 / HSD17B1 / hydroxysteroid 17-beta dehydrogenase 1ENSG0000010878641
DHRS7B / Q6IAN0 / dehydrogenase/reductase 7BENSG0000010901624
Q8NEX9 / SDR9C7 / short chain dehydrogenase/reductase family 9C member 7ENSG0000017042623
RDH5 / Q92781 / retinol dehydrogenase 5ENSG0000013543723
P80365 / HSD11B2 / hydroxysteroid 11-beta dehydrogenase 2ENSG0000017638722
RDH16 / O75452 / retinol dehydrogenase 16 (all-trans)ENSG0000013954722
DHRS7 / Q9Y394 / dehydrogenase/reductase 7ENSG0000010061222
BDH1 / Q02338 / 3-hydroxybutyrate dehydrogenase 1ENSG0000016126721
O14756 / HSD17B6 / hydroxysteroid 17-beta dehydrogenase 6ENSG0000002542321
KDSR / Q06136 / 3-ketodihydrosphingosine reductaseENSG0000011953721
DHRS9 / Q9BPW9 / dehydrogenase/reductase 9ENSG0000007373720
A6NNS2 / DHRS7C / dehydrogenase/reductase 7CENSG0000018454420
P37059 / HSD17B2 / hydroxysteroid 17-beta dehydrogenase 2ENSG0000008669618


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR011348  17beta-dehydrogenase
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006703 estrogen biosynthetic process IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004303 estradiol 17-beta-dehydrogenase activity IEA
 molecular_functionGO:0004745 retinol dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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