ENSG00000161267


Homo sapiens

Features
Gene ID: ENSG00000161267
  
Biological name :BDH1
  
Synonyms : 3-hydroxybutyrate dehydrogenase 1 / BDH1 / Q02338
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 197509783
Gene end: 197573323
  
Corresponding Affymetrix probe sets: 1570336_at (Human Genome U133 Plus 2.0 Array)   211715_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376184
Ensembl peptide - ENSP00000387648
Ensembl peptide - ENSP00000411014
Ensembl peptide - ENSP00000409849
Ensembl peptide - ENSP00000408685
Ensembl peptide - ENSP00000408016
Ensembl peptide - ENSP00000405462
Ensembl peptide - ENSP00000396149
Ensembl peptide - ENSP00000350914
Ensembl peptide - ENSP00000376183
NCBI entrez gene - 622     See in Manteia.
OMIM - 603063
RefSeq - XM_011513067
RefSeq - XM_017007011
RefSeq - XM_005269352
RefSeq - XM_017007010
RefSeq - XM_017007009
RefSeq - XM_017007008
RefSeq - XM_017007007
RefSeq - NM_004051
RefSeq - NM_203314
RefSeq - NM_203315
RefSeq - XM_017007012
RefSeq Peptide - NP_976059
RefSeq Peptide - NP_004042
RefSeq Peptide - NP_976060
swissprot - Q02338
swissprot - E9PCG9
swissprot - H7C2W1
swissprot - C9JB83
swissprot - C9JEB9
swissprot - C9JM78
swissprot - C9JQ90
swissprot - C9K0G7
Ensembl - ENSG00000161267
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bdh1ENSDARG00000059388Danio rerio
 BDH1AENSGALG00000006947Gallus gallus
 Bdh1ENSMUSG00000046598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O14756 / HSD17B6 / hydroxysteroid 17-beta dehydrogenase 6ENSG0000002542334
P37059 / HSD17B2 / hydroxysteroid 17-beta dehydrogenase 2ENSG0000008669632
RDH16 / O75452 / retinol dehydrogenase 16 (all-trans)ENSG0000013954732
Q8NEX9 / SDR9C7 / short chain dehydrogenase/reductase family 9C member 7ENSG0000017042631
P80365 / HSD11B2 / hydroxysteroid 11-beta dehydrogenase 2ENSG0000017638730
DHRS9 / Q9BPW9 / dehydrogenase/reductase 9ENSG0000007373730
RDH5 / Q92781 / retinol dehydrogenase 5ENSG0000013543729
P14061 / HSD17B1 / hydroxysteroid 17-beta dehydrogenase 1ENSG0000010878621
DHRS7B / Q6IAN0 / dehydrogenase/reductase 7BENSG0000010901620
RDH8 / retinol dehydrogenase 8 (all-trans)ENSG0000008051120
DHRS7 / Q9Y394 / dehydrogenase/reductase 7ENSG0000010061219
A6NNS2 / DHRS7C / dehydrogenase/reductase 7CENSG0000018454418
KDSR / Q06136 / 3-ketodihydrosphingosine reductaseENSG0000011953715


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0046951 ketone body biosynthetic process TAS
 biological_processGO:0046952 ketone body catabolic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0099617 matrix side of mitochondrial inner membrane ISS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003858 3-hydroxybutyrate dehydrogenase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Utilization of Ketone Bodies
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000161267 BDH1 / Q02338 / 3-hydroxybutyrate dehydrogenase 1  / complex






 

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