ENSG00000139547


Homo sapiens

Features
Gene ID: ENSG00000139547
  
Biological name :RDH16
  
Synonyms : O75452 / RDH16 / retinol dehydrogenase 16 (all-trans)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.3
Gene start: 56951431
Gene end: 56959374
  
Corresponding Affymetrix probe sets: 206753_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381206
NCBI entrez gene - 8608     See in Manteia.
RefSeq - NM_003708
RefSeq - NM_001320108
RefSeq Peptide - NP_001307037
RefSeq Peptide - NP_003699
swissprot - O75452
Ensembl - ENSG00000139547
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Rdh1ENSMUSG00000089789Mus musculus
 Rdh16ENSMUSG00000069456Mus musculus
 Rdh16f1ENSMUSG00000099009Mus musculus
 Rdh16f2ENSMUSG00000074639Mus musculus
 Rdh19ENSMUSG00000054052Mus musculus
 Rdh7ENSMUSG00000040134Mus musculus
 Rdh9ENSMUSG00000056148Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O14756 / HSD17B6 / hydroxysteroid 17-beta dehydrogenase 6ENSG0000002542366
RDH5 / Q92781 / retinol dehydrogenase 5ENSG0000013543752
Q8NEX9 / SDR9C7 / short chain dehydrogenase/reductase family 9C member 7ENSG0000017042651
DHRS9 / Q9BPW9 / dehydrogenase/reductase 9ENSG0000007373746
BDH1 / Q02338 / 3-hydroxybutyrate dehydrogenase 1ENSG0000016126735
P80365 / HSD11B2 / hydroxysteroid 11-beta dehydrogenase 2ENSG0000017638735
P37059 / HSD17B2 / hydroxysteroid 17-beta dehydrogenase 2ENSG0000008669634
P14061 / HSD17B1 / hydroxysteroid 17-beta dehydrogenase 1ENSG0000010878628
RDH8 / retinol dehydrogenase 8 (all-trans)ENSG0000008051123
DHRS7 / Q9Y394 / dehydrogenase/reductase 7ENSG0000010061223
DHRS7B / Q6IAN0 / dehydrogenase/reductase 7BENSG0000010901621
A6NNS2 / DHRS7C / dehydrogenase/reductase 7CENSG0000018454418
KDSR / Q06136 / 3-ketodihydrosphingosine reductaseENSG0000011953717


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle TAS
 molecular_functionGO:0004745 retinol dehydrogenase activity TAS
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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