ENSMUSG00000069456


Mus musculus

Features
Gene ID: ENSMUSG00000069456
  
Biological name :Rdh16
  
Synonyms : Rdh16 / retinol dehydrogenase 16
  
Possible biological names infered from orthology : O75452 / retinol dehydrogenase 16 (all-trans)
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 127801152
Gene end: 127846565
  
Corresponding Affymetrix probe sets: 10367045 (MoGene1.0st)   10367050 (MoGene1.0st)   1420541_at (Mouse Genome 430 2.0 Array)   1445728_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071573
Ensembl peptide - ENSMUSP00000122839
Ensembl peptide - ENSMUSP00000115993
NCBI entrez gene - 19683     See in Manteia.
MGI - MGI:1201375
RefSeq - NM_009040
RefSeq - XM_006513389
RefSeq Peptide - NP_033066
swissprot - D6RFT0
swissprot - O54909
swissprot - D6RFQ4
Ensembl - ENSMUSG00000069456
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RDH16ENSG00000139547Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rdh16f1 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000009900996
Rdh9 / retinol dehydrogenase 9 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005614895
Rdh19 / retinol dehydrogenase 19 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005405291
Rdh1 / retinol dehydrogenase 1 (all trans) / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000008978991
Rdh16f2 / RDH16 family member 2 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000007463989
Rdh7 / O88451 / Retinol dehydrogenase 7 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000004013482
Q9R092 / Hsd17b6 / Mus musculus hydroxysteroid (17-beta) dehydrogenase 6 (Hsd17b6), transcript variant 2, mRNA. / O14756* / hydroxysteroid 17-beta dehydrogenase 6*ENSMUSG0000002539666
Q8K3P0 / Sdr9c7 / 4short chain dehydrogenase/reductase family 9C, member 7 / Q8NEX9* / short chain dehydrogenase/reductase family 9C member 7*ENSMUSG0000004012752
Rdh5 / O55240 / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA. / Q92781* / retinol dehydrogenase 5*ENSMUSG0000002535051
Dhrs9 / Q58NB6 / Dehydrogenase/reductase SDR family member 9 / Q9BPW9* / dehydrogenase/reductase 9*ENSMUSG0000002706848
P51658 / Hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059*ENSMUSG0000003184437
Bdh1 / Q80XN0 / D-beta-hydroxybutyrate dehydrogenase, mitochondrial / Q02338* / 3-hydroxybutyrate dehydrogenase 1*ENSMUSG0000004659836
P51661 / Hsd11b2 / hydroxysteroid 11-beta dehydrogenase 2 / P80365*ENSMUSG0000003189135
P51656 / Hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061*ENSMUSG0000001930126
Rdh8 / retinol dehydrogenase 8 (all-trans)ENSMUSG0000005377323
Dhrs7 / Q9CXR1 / Dehydrogenase/reductase SDR family member 7 / Q9Y394* / dehydrogenase/reductase 7*ENSMUSG0000002109422
Dhrs7b / Q99J47 / Dehydrogenase/reductase SDR family member 7B / Q6IAN0* / dehydrogenase/reductase 7B*ENSMUSG0000004256920
Gm4756ENSMUSG0000010948219
Dhrs7c / Q8CHS7 / Dehydrogenase/reductase SDR family member 7C / A6NNS2* / dehydrogenase/reductase 7C*ENSMUSG0000003304418
Kdsr / Q6GV12 / 3-ketodihydrosphingosine reductase / Q06136*ENSMUSG0000000990517


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042904 9-cis-retinoic acid biosynthetic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IDA
 cellular_componentGO:0031301 integral component of organelle membrane IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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