ENSMUSG00000042569


Mus musculus

Features
Gene ID: ENSMUSG00000042569
  
Biological name :Dhrs7b
  
Synonyms : Dehydrogenase/reductase SDR family member 7B / Dhrs7b / Q99J47
  
Possible biological names infered from orthology : dehydrogenase/reductase 7B / Q6IAN0
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B2
Gene start: 60830631
Gene end: 60860195
  
Corresponding Affymetrix probe sets: 10376726 (MoGene1.0st)   1424869_at (Mouse Genome 430 2.0 Array)   1442661_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044924
Ensembl peptide - ENSMUSP00000104358
NCBI entrez gene - 216820     See in Manteia.
MGI - MGI:2384931
RefSeq - NM_145428
RefSeq - NM_001172112
RefSeq - XM_006532869
RefSeq Peptide - NP_001165583
RefSeq Peptide - NP_663403
swissprot - Q99J47
swissprot - Z4YKT6
swissprot - I7DM66
Ensembl - ENSMUSG00000042569
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhrs7bENSDARG00000075726Danio rerio
 DHRS7BENSGALG00000004759Gallus gallus
 DHRS7BENSG00000109016Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dhrs7c / Q8CHS7 / Dehydrogenase/reductase SDR family member 7C / A6NNS2* / dehydrogenase/reductase 7C*ENSMUSG0000003304440
Dhrs7 / Q9CXR1 / Dehydrogenase/reductase SDR family member 7 / Q9Y394* / dehydrogenase/reductase 7*ENSMUSG0000002109429
Gm4756ENSMUSG0000010948229
Rdh8 / retinol dehydrogenase 8 (all-trans)ENSMUSG0000005377324
Kdsr / Q6GV12 / 3-ketodihydrosphingosine reductase / Q06136*ENSMUSG0000000990523
P51658 / Hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059*ENSMUSG0000003184422
Rdh16f2 / RDH16 family member 2 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000007463920
Bdh1 / Q80XN0 / D-beta-hydroxybutyrate dehydrogenase, mitochondrial / Q02338* / 3-hydroxybutyrate dehydrogenase 1*ENSMUSG0000004659820
Rdh19 / retinol dehydrogenase 19 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005405220
P51656 / Hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061*ENSMUSG0000001930120
Rdh1 / retinol dehydrogenase 1 (all trans) / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000008978920
Rdh16f1 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000009900919
Rdh16 / retinol dehydrogenase 16 / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000006945619
Dhrs9 / Q58NB6 / Dehydrogenase/reductase SDR family member 9 / Q9BPW9* / dehydrogenase/reductase 9*ENSMUSG0000002706819
Rdh7 / O88451 / Retinol dehydrogenase 7 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000004013419
Q9R092 / Hsd17b6 / Mus musculus hydroxysteroid (17-beta) dehydrogenase 6 (Hsd17b6), transcript variant 2, mRNA. / O14756* / hydroxysteroid 17-beta dehydrogenase 6*ENSMUSG0000002539619
P51661 / Hsd11b2 / hydroxysteroid 11-beta dehydrogenase 2 / P80365*ENSMUSG0000003189119
Rdh9 / retinol dehydrogenase 9 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005614819
Rdh5 / O55240 / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA. / Q92781* / retinol dehydrogenase 5*ENSMUSG0000002535018
Q8K3P0 / Sdr9c7 / 4short chain dehydrogenase/reductase family 9C, member 7 / Q8NEX9* / short chain dehydrogenase/reductase family 9C member 7*ENSMUSG0000004012717


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003644 thymus atrophy "wasting of the thymus resulting in reduced size " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004545 enlarged esophagus "increased size of the part of the digestive canal through which food passes from the pharynx to the stomach" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010788 stomach hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the stomach" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nhej1tm1.1Ics/Nhej1tm1.1Ics,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr