ENSMUSG00000089789


Mus musculus

Features
Gene ID: ENSMUSG00000089789
  
Biological name :Rdh1
  
Synonyms : Rdh1 / retinol dehydrogenase 1 (all trans)
  
Possible biological names infered from orthology : O75452 / RDH16 / retinol dehydrogenase 16 (all-trans)
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 127759721
Gene end: 127768297
  
Corresponding Affymetrix probe sets: 10367036 (MoGene1.0st)   1421702_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073322
NCBI entrez gene - 107605     See in Manteia.
MGI - MGI:1195275
RefSeq - NM_080436
RefSeq - XM_006513030
RefSeq Peptide - NP_536684
swissprot - Q8CGV4
Ensembl - ENSMUSG00000089789
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RDH16ENSG00000139547Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rdh16f1 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000009900991
Rdh16 / retinol dehydrogenase 16 / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000006945691
Rdh19 / retinol dehydrogenase 19 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005405289
Rdh9 / retinol dehydrogenase 9 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000005614889
Rdh16f2 / RDH16 family member 2 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000007463986
Rdh7 / O88451 / Retinol dehydrogenase 7 / RDH16* / O75452* / retinol dehydrogenase 16 (all-trans)*ENSMUSG0000004013482
Q9R092 / Hsd17b6 / Mus musculus hydroxysteroid (17-beta) dehydrogenase 6 (Hsd17b6), transcript variant 2, mRNA. / O14756* / hydroxysteroid 17-beta dehydrogenase 6*ENSMUSG0000002539668
Rdh5 / O55240 / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA. / Q92781* / retinol dehydrogenase 5*ENSMUSG0000002535052
Q8K3P0 / Sdr9c7 / 4short chain dehydrogenase/reductase family 9C, member 7 / Q8NEX9* / short chain dehydrogenase/reductase family 9C member 7*ENSMUSG0000004012752
Dhrs9 / Q58NB6 / Dehydrogenase/reductase SDR family member 9 / Q9BPW9* / dehydrogenase/reductase 9*ENSMUSG0000002706848
P51658 / Hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059*ENSMUSG0000003184437
Bdh1 / Q80XN0 / D-beta-hydroxybutyrate dehydrogenase, mitochondrial / Q02338* / 3-hydroxybutyrate dehydrogenase 1*ENSMUSG0000004659836
P51661 / Hsd11b2 / hydroxysteroid 11-beta dehydrogenase 2 / P80365*ENSMUSG0000003189134
P51656 / Hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061*ENSMUSG0000001930126
Rdh8 / retinol dehydrogenase 8 (all-trans)ENSMUSG0000005377322
Dhrs7 / Q9CXR1 / Dehydrogenase/reductase SDR family member 7 / Q9Y394* / dehydrogenase/reductase 7*ENSMUSG0000002109422
Dhrs7b / Q99J47 / Dehydrogenase/reductase SDR family member 7B / Q6IAN0* / dehydrogenase/reductase 7B*ENSMUSG0000004256920
Gm4756ENSMUSG0000010948219
Dhrs7c / Q8CHS7 / Dehydrogenase/reductase SDR family member 7C / A6NNS2* / dehydrogenase/reductase 7C*ENSMUSG0000003304418
Kdsr / Q6GV12 / 3-ketodihydrosphingosine reductase / Q06136*ENSMUSG0000000990516


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process IDA
 biological_processGO:0008202 steroid metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0016229 steroid dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000683 decreased percent water in carcass "less than the normal total amount of water retained in the body measured post mortem" [il:Ira Lu, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001257 increased body length "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003917 increased kidney weight "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008908 increased total fat pad weight "greater than average weight of the fat pads" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011234 abnormal retinol level "any anomaly in the concentration of retinol, which plays an essential role in metabolic functioning of the retina, and growth and differentiation" [ISBN:0-683-40008-8]
Show

Allelic Composition: Ace2tm1Hira/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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