ENSDARG00000027469


Danio rerio

Features
Gene ID: ENSDARG00000027469
  
Biological name :hsd17b1
  
Synonyms : hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1
  
Possible biological names infered from orthology : P14061 / P51656
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 18038972
Gene end: 18047150
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000026566
NCBI entrez gene - 402842     See in Manteia.
swissprot - F1QUP2
ZFIN ID - ZDB-GENE-040901-5
Ensembl - ENSDARG00000027469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD17B1ENSGALG00000027429Gallus gallus
 P14061ENSG00000108786Homo sapiens
 P51656ENSMUSG00000019301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rdh8b / retinol dehydrogenase 8b / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000010506041
zgc:109982ENSDARG0000009921741
rdh8a / retinol dehydrogenase 8a / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000002804840
zmp:0000001048ENSDARG0000001621337
rdh1 / retinol dehydrogenase 1ENSDARG0000001788228
rdh5 / retinol dehydrogenase 5 (11-cis/9-cis) / Q92781* / O55240* / retinol dehydrogenase 5* / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA.*ENSDARG0000000830625
hsd11b2 / hydroxysteroid (11-beta) dehydrogenase 2 / P51661* / P80365*ENSDARG0000000197524
zgc:113142ENSDARG0000003896924
bdh1 / 3-hydroxybutyrate dehydrogenase, type 1 / Q80XN0* / Q02338* / 3-hydroxybutyrate dehydrogenase 1* / D-beta-hydroxybutyrate dehydrogenase, mitochondrial *ENSDARG0000005938822
A8E5C5 / dhrs7cb / dehydrogenase/reductase (SDR family) member 7Cb / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000007187721
dhrs9 / dehydrogenase/reductase (SDR family) member 9 / Q58NB6* / Q9BPW9* / dehydrogenase/reductase 9*ENSDARG0000001926021
dhrs7b / dehydrogenase/reductase (SDR family) member 7B / Q6IAN0* / Q99J47* / dehydrogenase/reductase 7B*ENSDARG0000007572621
dhrs7 / dehydrogenase/reductase (SDR family) member 7 / Gm4756* / Q9CXR1* / Q9Y394* / dehydrogenase/reductase 7*ENSDARG0000000344421
dhrs7ca / dehydrogenase/reductase (SDR family) member 7Ca / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000003945320
kdsr / 3-ketodihydrosphingosine reductase / Q06136* / Q6GV12*ENSDARG0000001202120
hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059* / P51658*ENSDARG0000004555320


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR011348  17beta-dehydrogenase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006703 estrogen biosynthetic process IDA
 biological_processGO:0008209 androgen metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004303 estradiol 17-beta-dehydrogenase activity IDA
 molecular_functionGO:0016229 steroid dehydrogenase activity IDA


Pathways (from Reactome)
Pathway description
Estrogen biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027469 hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061* / P51656*  / complex






 

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