ENSDARG00000003020


Danio rerio

Features
Gene ID: ENSDARG00000003020
  
Biological name :lrrc4.2
  
Synonyms : leucine rich repeat containing 4.2 / lrrc4.2
  
Possible biological names infered from orthology : leucine rich repeat containing 4 / Leucine-rich repeat-containing protein 4 / LRRC4 / Q99PH1 / Q9HBW1
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 10296228
Gene end: 10298162
  
Corresponding Affymetrix probe sets: Dr.14786.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000005494
NCBI entrez gene - 566572     See in Manteia.
RefSeq - NM_001100024
RefSeq Peptide - NP_001093494
swissprot - A5WVM1
ZFIN ID - ZDB-GENE-030131-7997
Ensembl - ENSDARG00000003020
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRC4ENSG00000128594Homo sapiens
 Lrrc4ENSMUSG00000049939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lrrc4.1 / leucine rich repeat containing 4.1 / LRRC4* / Q99PH1* / Q9HBW1* / leucine rich repeat containing 4* / Leucine-rich repeat-containing protein 4 *ENSDARG0000006940274
lrrc4c / leucine rich repeat containing 4C / Q9HCJ2*ENSDARG0000011341153
lrrc4ba / leucine rich repeat containing 4Ba / Q9NT99* / LRRC4B* / P0C192* / leucine rich repeat containing 4B* / Leucine-rich repeat-containing protein 4B *ENSDARG0000000459753
si:dkey-6l15.1 / LRRC4C (1 of many) / LRRC4C* / Q8C031* / Q9HCJ2* / leucine rich repeat containing 4C* / Leucine-rich repeat-containing protein 4C *ENSDARG0000001673952
lrrc4bb / leucine rich repeat containing 4Bb / Q9NT99* / LRRC4B* / P0C192* / leucine rich repeat containing 4B* / Leucine-rich repeat-containing protein 4B *ENSDARG0000001479252
lingo4a / leucine rich repeat and Ig domain containing 4a / LINGO4* / Q6UY18* / leucine rich repeat and Ig domain containing 4*ENSDARG0000009490823
Q66HV9 / lingo1b / leucine rich repeat and Ig domain containing 1b / Q9D1T0* / LINGO1* / Q96FE5* / leucine rich repeat and Ig domain containing 1* / Leucine-rich repeat and immunoglobulin-l...ENSDARG0000003589923
lingo2b / leucine rich repeat and Ig domain containing 2b / LINGO2* / Q7L985* / Q3URE9* / leucine rich repeat and Ig domain containing 2*ENSDARG0000006997022
CABZ01060891.1 / LINGO3* / P0C6S8* / leucine rich repeat and Ig domain containing 3*ENSDARG0000006781522
lingo2a / leucine rich repeat and Ig domain containing 2a / LINGO2* / Q7L985* / Q3URE9* / leucine rich repeat and Ig domain containing 2*ENSDARG0000007453522
lingo1a / leucine rich repeat and Ig domain containing 1a / Q9D1T0* / LINGO1* / Q96FE5* / leucine rich repeat and Ig domain containing 1* / Leucine-rich repeat and immunoglobulin-like domai...ENSDARG0000003416522
lrfn4b / leucine rich repeat and fibronectin type III domain containing 4b / LRFN4* / Q6PJG9* / Q80XU8* / leucine rich repeat and fibronectin type III domain containing 4* / Leucine-rich re...ENSDARG0000007807821
lrrn1 / leucine rich repeat neuronal 1 / Q61809* / Q6UXK5* / Leucine-rich repeat neuronal protein 1 *ENSDARG0000006011521
lingo3a / leucine rich repeat and Ig domain containing 3a / Q6GQU6* / LINGO3* / P0C6S8* / leucine rich repeat and Ig domain containing 3* / Leucine-rich repeat and immunoglobulin-like domai...ENSDARG0000006197021
lingo4b / leucine rich repeat and Ig domain containing 4b / LINGO4* / Q6UY18* / leucine rich repeat and Ig domain containing 4*ENSDARG0000007852721
si:ch211-180f4.1ENSDARG0000007711221
lrfn2b / leucine rich repeat and fibronectin type III domain containing 2b / LRFN2* / Q80TG9* / Q9ULH4* / leucine rich repeat and fibronectin type III domain containing 2* / Leucine-rich re...ENSDARG0000007748920
lrfn5b / leucine rich repeat and fibronectin type III domain containing 5b / LRFN5* / Q8BXA0* / Q96NI6* / leucine rich repeat and fibronectin type III domain containing 5* / Leucine-rich re...ENSDARG0000007939620
lrfn5a / leucine rich repeat and fibronectin type III domain containing 5a / LRFN5* / Q8BXA0* / Q96NI6* / leucine rich repeat and fibronectin type III domain containing 5* / Leucine-rich re...ENSDARG0000007123020
lrfn4a / leucine rich repeat and fibronectin type III domain containing 4a / LRFN4* / Q6PJG9* / Q80XU8* / leucine rich repeat and fibronectin type III domain containing 4* / Leucine-rich re...ENSDARG0000005513220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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