ENSDARG00000003022


Danio rerio

Features
Gene ID: ENSDARG00000003022
  
Biological name :limk1b
  
Synonyms : LIM domain kinase 1b / limk1b
  
Possible biological names infered from orthology : LIM domain kinase 1 / LIMK1 / P53667 / P53668
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 40805336
Gene end: 40835069
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000021697
Ensembl peptide - ENSDARP00000123970
NCBI entrez gene - 101883214     See in Manteia.
swissprot - E7FB16
swissprot - F8W473
ZFIN ID - ZDB-GENE-110411-106
Ensembl - ENSDARG00000003022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LIMK1ENSGALG00000001076Gallus gallus
 LIMK1ENSG00000106683Homo sapiens
 Limk1ENSMUSG00000029674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
limk1a / LIM domain kinase 1a / LIMK1* / P53667* / LIM domain kinase 1*ENSDARG0000010346756
limk2 / LIM domain kinase 2 / O54785* / P53671*ENSDARG0000000510448
si:ch211-113e8.3 / TESK1* / Q15569* / O70146* / testis-specific kinase 1* / Dual specificity testis-specific protein kinase 1 *ENSDARG0000007825120
si:dkeyp-75h12.2 / TESK1* / Q15569* / O70146* / testis-specific kinase 1* / Dual specificity testis-specific protein kinase 1 *ENSDARG0000007928120
tesk2 / testis-specific kinase 2 / Q8VCT9* / Q96S53* / Dual specificity testis-specific protein kinase 2 *ENSDARG0000006145018
zgc:113162ENSDARG0000005292318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001478  PDZ domain
 IPR001781  Zinc finger, LIM-type
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0051496 positive regulation of stress fiber assembly IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
Sema3A PAK dependent Axon repulsion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003022 limk1b / LIM domain kinase 1b / LIMK1* / P53667* / P53668* / LIM domain kinase 1*  / complex / reaction
 ENSDARG00000010478 Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...  / reaction / complex






 

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