ENSDARG00000004227


Danio rerio

Features
Gene ID: ENSDARG00000004227
  
Biological name :pde3a
  
Synonyms : pde3a / phosphodiesterase 3A, cGMP-inhibited
  
Possible biological names infered from orthology : phosphodiesterase 3A / Q14432 / Q9Z0X4
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 2752852
Gene end: 2868112
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119110
Ensembl peptide - ENSDARP00000133613
NCBI entrez gene - 567051     See in Manteia.
swissprot - A0A0R4IEP8
swissprot - F6P4K3
ZFIN ID - ZDB-GENE-041210-23
Ensembl - ENSDARG00000004227
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE3AENSGALG00000013143Gallus gallus
 PDE3AENSG00000172572Homo sapiens
 Pde3aENSMUSG00000041741Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE3B / si:ch211-79e4.4 / Q13370* / phosphodiesterase 3B*ENSDARG0000006219041
pde6b / phosphodiesterase 6B, cGMP-specific, rod, beta / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide*ENSDARG0000001167114
pde6a / phosphodiesterase 6A, cGMP-specific, rod, alpha / P16499* / phosphodiesterase 6A*ENSDARG0000000038014
pde6c / phosphodiesterase 6C, cGMP-specific, cone, alpha prime / P51160* / Q91ZQ1* / phosphodiesterase 6C* / Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha *ENSDARG0000010039713
pde5ab / phosphodiesterase 5A, cGMP-specific, b / PDE5A* / Q8CG03* / O76074* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase *ENSDARG0000005191512
pde11al / phosphodiesterase 11a, likeENSDARG0000000615112
pde11a / phosphodiesterase 11a / P0C1Q2* / Q9HCR9* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A *ENSDARG0000006373212
FQ378016.1 / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000010893911
pde9a / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A *ENSDARG0000006028011
pde9al / phosphodiesterase 9A like / PDE9A* / O76083* / phosphodiesterase 9A*ENSDARG0000007665011
pde10a / phosphodiesterase 10A / Q8CA95* / Q9Y233*ENSDARG0000000344910
si:dkey-219c10.4ENSDARG000000759299
pde5aa / phosphodiesterase 5A, cGMP-specific, aENSDARG000000568064
CABZ01079080.1 / PDE2A* / O00408* / phosphodiesterase 2A*ENSDARG000000790643


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
cGMP effects
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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