ENSDARG00000100397
Danio rerio | |
Features
| Gene ID: | ENSDARG00000100397 | | | | | Biological name : | pde6c | | | | | Synonyms : | pde6c / phosphodiesterase 6C, cGMP-specific, cone, alpha prime | | | | | Possible biological names infered from orthology : | Cone cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha / P51160 / phosphodiesterase 6C / Q91ZQ1 | | | | | Species: | Danio rerio | | | | | Chr. number: | 12 | | Strand: | 1 | | Band: | | | Gene start: | 5129245 | | Gene end: | 5154099 | | | | | Corresponding Affymetrix probe sets: | Dr.9841.1.A1_at (Zebrafish Array) NM_200871_at (Zebrafish Genome Array with custom cdf files) | | | | | Cross references: | Ensembl peptide - ENSDARP00000138871
NCBI entrez gene - 393845
See in Manteia.
RefSeq - NM_200871
RefSeq Peptide - NP_957165
swissprot - A0A0R4IUY2
ZFIN ID - ZDB-GENE-040426-1664
Ensembl - ENSDARG00000100397
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See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
| pde6b / phosphodiesterase 6B, cGMP-specific, rod, beta / P35913* / P23440* / phosphodiesterase 6B* / phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide* | ENSDARG00000011671 | 62 | | pde6a / phosphodiesterase 6A, cGMP-specific, rod, alpha / P16499* / phosphodiesterase 6A* | ENSDARG00000000380 | 61 | | pde11al / phosphodiesterase 11a, like | ENSDARG00000006151 | 30 | | pde11a / phosphodiesterase 11a / P0C1Q2* / Q9HCR9* / Dual 3,5-cyclic-AMP and -GMP phosphodiesterase 11A * | ENSDARG00000063732 | 29 | | pde5ab / phosphodiesterase 5A, cGMP-specific, b / PDE5A* / Q8CG03* / O76074* / phosphodiesterase 5A* / cGMP-specific 3,5-cyclic phosphodiesterase * | ENSDARG00000051915 | 28 | | pde10a / phosphodiesterase 10A / Q8CA95* / Q9Y233* | ENSDARG00000003449 | 21 | | pde3a / phosphodiesterase 3A, cGMP-inhibited / Q14432* / Q9Z0X4* / phosphodiesterase 3A* | ENSDARG00000004227 | 17 | | PDE3B / si:ch211-79e4.4 / Q13370* / phosphodiesterase 3B* | ENSDARG00000062190 | 16 | | pde9al / phosphodiesterase 9A like / PDE9A* / O76083* / phosphodiesterase 9A* | ENSDARG00000076650 | 15 | | pde9a / phosphodiesterase 9A / O70628* / O76083* / High affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A * | ENSDARG00000060280 | 15 | | FQ378016.1 / PDE9A* / O76083* / phosphodiesterase 9A* | ENSDARG00000108939 | 15 | | si:dkey-219c10.4 | ENSDARG00000075929 | 11 | | pde5aa / phosphodiesterase 5A, cGMP-specific, a | ENSDARG00000056806 | 7 | | CABZ01079080.1 / PDE2A* / O00408* / phosphodiesterase 2A* | ENSDARG00000079064 | 4 |
Protein motifs (from Interpro)
| IPR002073 | 3"5"-cyclic nucleotide phosphodiesterase, catalytic domain | | IPR003018 | GAF domain | | IPR003607 | HD/PDEase domain | | IPR023088 | 3"5"-cyclic nucleotide phosphodiesterase | | IPR023174 | 3"5"-cyclic nucleotide phosphodiesterase, conserved site | | IPR029016 | GAF-like domain superfamily |
Gene Ontology (GO)
Pathways (from Reactome)
No match
Phenotype (from MGI, Zfin or HPO)
| ZFA:0000037 | anatomical structure | anatomical structure decreased amount , abnormal |
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| | ZFA:0000107 | eye | eye apoptotic , abnormal |
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| | ZFA:0000119 | retinal inner nuclear layer | retinal inner nuclear layer cell decreased amount , abnormal |
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| | ZFA:0000143 | retinal photoreceptor layer | retinal photoreceptor layer morphology , abnormal |
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| | ZFA:0000152 | retina | retina photoreceptor cell degenerate , abnormal
retina has fewer parts of type retinal cone cell , abnormal |
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| | ZFA:0001330 | retinal outer plexiform layer | retinal outer plexiform layer has fewer parts of type neuron synapse, abnormal
retinal outer plexiform layer disorganized , abnormal
retinal outer plexiform layer morphology , abnormal
retinal outer plexiform layer irregular thickness , abnormal |
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| | ZFA:0001464 | retinal outer nuclear layer | retinal outer nuclear layer disorganized , abnormal |
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| | ZFA:0009154 | eye photoreceptor cell | eye photoreceptor cell photoreceptor outer segment morphology , abnormal |
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| | ZFA:0009221 | UV sensitive photoreceptor cell | UV sensitive photoreceptor cell decreased amount , abnormal |
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| | ZFA:0009222 | blue sensitive photoreceptor cell | blue sensitive photoreceptor cell decreased amount , abnormal |
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| | ZFA:0009223 | green sensitive photoreceptor cell | green sensitive photoreceptor cell decreased amount , abnormal |
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| | ZFA:0009224 | red sensitive photoreceptor cell | red sensitive photoreceptor cell decreased amount , abnormal |
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| | ZFA:0009262 | retinal cone cell | retinal cone cell decreased amount , abnormal
retinal cone cell morphology , abnormal
retinal cone cell degenerate , abnormal
retinal cone cell cell death increased process quality , abnormal |
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| | ZFA:0009275 | retinal rod cell | retinal rod cell photoreceptor outer segment morphology , abnormal
retinal rod cell degenerate , abnormal
retinal rod cell increased volume , abnormal
retinal rod cell increased volume , ameliorated
retinal rod cell morphology , abnormal |
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| | ZFA:0009280 | Muller cell | Muller cell morphology , abnormal |
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| | ZFA:0009318 | retinal bipolar neuron | retinal bipolar neuron nucleus displaced , abnormal
retinal bipolar neuron axon displaced , abnormal |
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| | ZFA:0009319 | ON-bipolar cell | ON-bipolar cell axon increased amount , abnormal
ON-bipolar cell dendrite increased amount , abnormal
ON-bipolar cell axon increased length , abnormal
ON-bipolar cell axon located in retinal ganglion cell layer , abnormal
ON-bipolar cell morphology , abnormal
ON-bipolar cell dendrite increased length , abnormal
ON-bipolar cell dendrite located in retinal outer nuclear layer , abnormal |
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Interacting proteins (from Reactome)
No match
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