ENSDARG00000005754


Danio rerio

Features
Gene ID: ENSDARG00000005754
  
Biological name :ptprfb
  
Synonyms : A4IFW2 / protein tyrosine phosphatase, receptor type, f, b / ptprfb
  
Possible biological names infered from orthology : A2A8L5 / P10586 / protein tyrosine phosphatase, receptor type F / PTPRF / Receptor-type tyrosine-protein phosphatase F
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 17578320
Gene end: 17947389
  
Corresponding Affymetrix probe sets: Dr.12854.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000155871
Ensembl peptide - ENSDARP00000156606
Ensembl peptide - ENSDARP00000156870
Ensembl peptide - ENSDARP00000077749
Ensembl peptide - ENSDARP00000113166
Ensembl peptide - ENSDARP00000132216
Ensembl peptide - ENSDARP00000151637
NCBI entrez gene - 799867     See in Manteia.
RefSeq - NM_001083576
RefSeq - XM_009298466
RefSeq - XM_009298467
RefSeq - XM_009298469
RefSeq - XM_021481419
RefSeq - XM_021481440
RefSeq - XM_009298460
RefSeq - XM_009298462
RefSeq - XM_009298464
RefSeq Peptide - NP_001077045
swissprot - A4IFW2
swissprot - F1RAP4
swissprot - A0A0R4IGS0
ZFIN ID - ZDB-GENE-060503-530
Ensembl - ENSDARG00000005754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRFENSGALG00000010053Gallus gallus
 PTPRFENSG00000142949Homo sapiens
 PtprfENSMUSG00000033295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptprfa / protein tyrosine phosphatase, receptor type, f, a / PTPRF* / A2A8L5* / P10586* / protein tyrosine phosphatase, receptor type F* / Receptor-type tyrosine-protein phosphatase F *ENSDARG0000010347984
ptprsa / protein tyrosine phosphatase, receptor type, s, a / PTPRS* / B0V2N1* / Q13332* / Receptor-type tyrosine-protein phosphatase S * / protein tyrosine phosphatase, receptor type S*ENSDARG0000005973863
ptprsa / protein tyrosine phosphatase, receptor type, s, a / PTPRS* / Q13332* / protein tyrosine phosphatase, receptor type S*ENSDARG0000011094030
ptprt / protein tyrosine phosphatase, receptor type, t / O14522* / Q99M80* / Receptor-type tyrosine-protein phosphatase T *ENSDARG0000007478120
ptprk / protein tyrosine phosphatase, receptor type, K / P35822* / Q15262*ENSDARG0000006341619
ptprua / protein tyrosine phosphatase, receptor type, U, a / PTPRU* / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSDARG0000009263819
ptprub / protein tyrosine phosphatase, receptor type, U, b / PTPRU* / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSDARG0000010108119
ptprz1a / protein tyrosine phosphatase, receptor-type, Z polypeptide 1a / B9EKR1* / P23471* / PTPRZ1* / protein tyrosine phosphatase, receptor type Z1* / protein tyrosine phosphatase, recep...ENSDARG0000005181418
ptprga / protein tyrosine phosphatase, receptor type, g a / PTPRG* / P23470* / protein tyrosine phosphatase, receptor type G*ENSDARG0000004500618
ca16b / carbonic anhydrase XVI b / PTPRG* / P23470* / protein tyrosine phosphatase, receptor type G* / receptor-type tyrosine-protein phosphatase gamma isoform 2 *ENSDARG0000006012317
ptpra / protein tyrosine phosphatase, receptor type, A / P18052* / P18433*ENSDARG0000000176917
ptprz1b / protein tyrosine phosphatase, receptor-type, Z polypeptide 1b / B9EKR1* / P23471* / PTPRZ1* / protein tyrosine phosphatase, receptor type Z1* / protein tyrosine phosphatase, recep...ENSDARG0000002087116
ptprea / protein tyrosine phosphatase, receptor type, E, a / PTPRE* / P49446* / P23469* / protein tyrosine phosphatase, receptor type E* / Receptor-type tyrosine-protein phosphatase epsilon *ENSDARG0000001589116
ptpreb / protein tyrosine phosphatase, receptor type, E, b / PTPRE* / P49446* / P23469* / protein tyrosine phosphatase, receptor type E* / Receptor-type tyrosine-protein phosphatase epsilon *ENSDARG0000002115115
ptprc / protein tyrosine phosphatase, receptor type, CENSDARG0000007143714
ptprt / protein tyrosine phosphatase, receptor type, t / O14522*ENSDARG0000009757213
CABZ01084131.1 / PTPRM* / P28827* / protein tyrosine phosphatase, receptor type M*ENSDARG000001147626
si:ch1073-391i24.1 / PTPRM* / P28827* / P28828* / protein tyrosine phosphatase, receptor type M*ENSDARG000000891726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0097374 sensory neuron axon guidance IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron axon mislocalized adaxially , abnormal
Rohon-Beard neuron axon subdermal , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014792 lrrc4bb / leucine rich repeat containing 4Bb / Q9NT99* / LRRC4B* / P0C192* / leucine rich repeat containing 4B* / Leucine-rich repeat-containing protein 4B *  / complex / reaction
 ENSDARG00000004597 lrrc4ba / leucine rich repeat containing 4Ba / Q9NT99* / LRRC4B* / P0C192* / leucine rich repeat containing 4B* / Leucine-rich repeat-containing protein 4B *  / complex / reaction
 ENSDARG00000055132 lrfn4a / leucine rich repeat and fibronectin type III domain containing 4a / LRFN4* / Q6PJG9* / Q80XU8* / leucine rich repeat and fibronectin type III domain containing 4* / Leucine-rich re...  / reaction / complex
 ENSDARG00000077053 ppfia3 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 / O75145* / P60469* / PTPRF interacting protein alpha 3*  / reaction / complex
 ENSDARG00000053205 ppfia4 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 / O75335* / PTPRF interacting protein alpha 4*  / reaction / complex
 ENSDARG00000013000 ppfia2 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 / O75334* / PTPRF interacting protein alpha 2*  / complex / reaction






 

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