ENSDARG00000006266


Danio rerio

Features
Gene ID: ENSDARG00000006266
  
Biological name :stat1a
  
Synonyms : signal transducer and activator of transcription 1a / stat1a
  
Possible biological names infered from orthology : P42224 / signal transducer and activator of transcription 1 / STAT1
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 12798569
Gene end: 12826962
  
Corresponding Affymetrix probe sets: Dr.257.1.A1_at (Zebrafish Array)   Dr.8151.2.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000015753
swissprot - Q6P943
ZFIN ID - ZDB-GENE-980526-499
Ensembl - ENSDARG00000006266
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAT1ENSGALG00000007651Gallus gallus
 STAT1ENSG00000115415Homo sapiens
 Stat1ENSMUSG00000026104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*ENSDARG0000007618252
stat4 / signal transducer and activator of transcription 4 / Q14765*ENSDARG0000002873148
stat3 / signal transducer and activator of transcription 3 (acute-phase response factor) / P40763* / P42227* / signal transducer and activator of transcription 3*ENSDARG0000002271247
stat2 / signal transducer and activator of transcription 2 / P52630*ENSDARG0000003164741
stat5a / signal transducer and activator of transcription 5a / P42232* / P51692* / STAT5B* / P42229* / P42230* / signal transducer and activator of transcription 5B*ENSDARG0000001939228
stat5b / signal transducer and activator of transcription 5b / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSDARG0000005558827
stat6 / signal transducer and activator of transcription 6, interleukin-4 induced / P42226* / P52633* / Signal transducer and transcription activator 6 * / signal transducer and activator o...ENSDARG0000001590225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil
 IPR022752  Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-6 signaling
ISG15 antiviral mechanism
Signaling by SCF-KIT
Downstream signal transduction
Interleukin-4 and Interleukin-13 signaling
Interferon gamma signaling
Regulation of IFNG signaling
Interleukin-20 family signaling
Interleukin-35 Signalling
Interleukin-9 signaling
Interleukin-27 signaling
Interleukin-21 signaling
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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