ENSDARG00000015902


Danio rerio

Features
Gene ID: ENSDARG00000015902
  
Biological name :stat6
  
Synonyms : signal transducer and activator of transcription 6, interleukin-4 induced / stat6
  
Possible biological names infered from orthology : P42226 / P52633 / signal transducer and activator of transcription 6 / Signal transducer and transcription activator 6
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 27078866
Gene end: 27123180
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000026606
Ensembl peptide - ENSDARP00000121041
Ensembl peptide - ENSDARP00000120532
NCBI entrez gene - 337413     See in Manteia.
swissprot - E9QCS5
swissprot - B3DGV1
swissprot - F1QLX8
ZFIN ID - ZDB-GENE-030131-9359
Ensembl - ENSDARG00000015902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAT6ENSG00000166888Homo sapiens
 Stat6ENSMUSG00000002147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stat5a / signal transducer and activator of transcription 5a / P42232* / P51692* / STAT5B* / P42229* / P42230* / signal transducer and activator of transcription 5B*ENSDARG0000001939234
stat5b / signal transducer and activator of transcription 5b / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSDARG0000005558834
stat4 / signal transducer and activator of transcription 4 / Q14765*ENSDARG0000002873126
stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*ENSDARG0000007618225
stat1a / signal transducer and activator of transcription 1a / STAT1* / P42224* / signal transducer and activator of transcription 1*ENSDARG0000000626625
stat2 / signal transducer and activator of transcription 2 / P52630*ENSDARG0000003164724
stat3 / signal transducer and activator of transcription 3 (acute-phase response factor) / P40763* / P42227* / signal transducer and activator of transcription 3*ENSDARG0000002271224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Downstream signal transduction
STAT6-mediated induction of chemokines
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015902 stat6 / signal transducer and activator of transcription 6, interleukin-4 induced / P42226* / P52633* / Signal transducer and transcription activator 6 * / signal transducer and activator o...  / complex / reaction
 ENSDARG00000091058 tmem173 / transmembrane protein 173 / Q3TBT3* / Q86WV6* / Stimulator of interferons protein *  / reaction / complex
 ENSDARG00000103095 tbk1 / TANK-binding kinase 1 / Q9UHD2*  / reaction / complex






 

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