ENSDARG00000031647


Danio rerio

Features
Gene ID: ENSDARG00000031647
  
Biological name :stat2
  
Synonyms : signal transducer and activator of transcription 2 / stat2
  
Possible biological names infered from orthology : P52630
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 39123544
Gene end: 39160422
  
Corresponding Affymetrix probe sets: Dr.11946.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124003
Ensembl peptide - ENSDARP00000050681
NCBI entrez gene - 565200     See in Manteia.
RefSeq - NM_001271801
RefSeq - XM_005166048
RefSeq - XM_017356505
RefSeq Peptide - NP_001258730
swissprot - F8W3X1
swissprot - E7FBV9
ZFIN ID - ZDB-GENE-080321-1
Ensembl - ENSDARG00000031647
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAT2ENSGALG00000030661Gallus gallus
 STAT2ENSG00000170581Homo sapiens
 Stat2ENSMUSG00000040033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stat3 / signal transducer and activator of transcription 3 (acute-phase response factor) / P40763* / P42227* / signal transducer and activator of transcription 3*ENSDARG0000002271240
stat1a / signal transducer and activator of transcription 1a / STAT1* / P42224* / signal transducer and activator of transcription 1*ENSDARG0000000626637
stat4 / signal transducer and activator of transcription 4 / Q14765*ENSDARG0000002873136
stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*ENSDARG0000007618233
stat5a / signal transducer and activator of transcription 5a / P42232* / P51692* / STAT5B* / P42229* / P42230* / signal transducer and activator of transcription 5B*ENSDARG0000001939225
stat5b / signal transducer and activator of transcription 5b / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSDARG0000005558825
stat6 / signal transducer and activator of transcription 6, interleukin-4 induced / P42226* / P52633* / Signal transducer and transcription activator 6 * / signal transducer and activator o...ENSDARG0000001590222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016457 irf9 / interferon regulatory factor 9 / Q00978* / Q61179*  / complex / reaction
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / complex






 

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