ENSGALG00000030661


Gallus gallus

Features
Gene ID: ENSGALG00000030661
  
Biological name :STAT2
  
Synonyms : signal transducer and activator of transcription 2 / STAT2
  
Possible biological names infered from orthology : P52630
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 767595
Gene end: 775109
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000051114
Ensembl peptide - ENSGALP00000052740
Ensembl peptide - ENSGALP00000051677
NCBI entrez gene - 100858732     See in Manteia.
RefSeq - XM_015300282
RefSeq - XM_015300283
RefSeq - XM_015300284
RefSeq - XM_015300285
swissprot - A0A1D5PIV4
swissprot - A0A1D5PEB3
Ensembl - ENSGALG00000030661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stat2ENSDARG00000031647Danio rerio
 STAT2ENSG00000170581Homo sapiens
 Stat2ENSMUSG00000040033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAT1 / signal transducer and activator of transcription 1 / P42224*ENSGALG0000000765133
STAT3 / Q6DV79 / Signal transducer and activator of transcription 3 / P40763* / P42227*ENSGALG0000000326732
STAT4 / signal transducer and activator of transcription 4 / Q14765*ENSGALG0000003308730
STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*ENSGALG0000000328220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001217  Transcription factor STAT
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011992  EF-hand domain pair
 IPR012345  STAT transcription factor, DNA-binding, N-terminal
 IPR013799  STAT transcription factor, protein interaction
 IPR013800  STAT transcription factor, all-alpha domain
 IPR013801  STAT transcription factor, DNA-binding
 IPR015988  STAT transcription factor, coiled coil


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060337 type I interferon signaling pathway IEA
 biological_processGO:0090140 regulation of mitochondrial fission IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling
Interferon alpha/beta signaling
Regulation of IFNA signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004821 PTPN11 / Q90687 / Tyrosine-protein phosphatase non-receptor type 11 / P35235* / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / reaction
 ENSGALG00000008010 PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*  / reaction
 ENSGALG00000007651 STAT1 / signal transducer and activator of transcription 1 / P42224*  / complex / reaction
 ENSGALG00000007158 SOCS1 / suppressor of cytokine signaling 1 / O15524* / O35716*  / complex
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000015062 IFNK* / IFNA6* / IFNA7* / IFNA8* / Ifna9* / Ifnab* / IFNW1* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / Q9P0W0* / IFNA10* / Ifna11* / Ifna12* / IFNA13* / IFNA14* / Ifna15* / IFNA16* / IFNA17* / I...  / complex / reaction
 ENSGALG00000014561 PTPN6 / tyrosine-protein phosphatase non-receptor type 6 / P29350* / P29351* / protein tyrosine phosphatase, non-receptor type 6*  / reaction
 ENSGALG00000030661 STAT2 / signal transducer and activator of transcription 2 / P52630*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr