ENSDARG00000006615


Danio rerio

Features
Gene ID: ENSDARG00000006615
  
Biological name :hnf1ba
  
Synonyms : hnf1ba / HNF1 homeobox Ba
  
Possible biological names infered from orthology : Hepatocyte nuclear factor 1-beta / HNF1B / HNF1 homeobox B / P27889 / P35680
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 15997149
Gene end: 16012963
  
Corresponding Affymetrix probe sets: Dr.14662.1.S1_at (Zebrafish Array)   Dr.14662.1.S2_at (Zebrafish Array)   NM_131880_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000119593
NCBI entrez gene - 792391     See in Manteia.
RefSeq - NM_131880
RefSeq Peptide - NP_571955
swissprot - E9QEC0
ZFIN ID - ZDB-GENE-020104-1
Ensembl - ENSDARG00000006615
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HNF1BENSGALG00000005504Gallus gallus
 HNF1BENSG00000275410Homo sapiens
 Hnf1bENSMUSG00000020679Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8UW00 / hnf1bb / HNF1 homeobox Bb / HNF1B* / P27889* / P35680* / HNF1 homeobox B* / Hepatocyte nuclear factor 1-beta *ENSDARG0000002229564
hnf1a / HNF1 homeobox aENSDARG0000000947043
zgc:91944ENSDARG0000003588715
CABZ01078261.1 / HMBOX1* / Q6NT76* / homeobox containing 1*ENSDARG0000010928715
hmbox1a / homeobox containing 1a / HMBOX1* / Q6NT76* / Q8BJA3* / homeobox containing 1* / Mus musculus homeobox containing 1 (Hmbox1), transcript variant 3, mRNA.*ENSDARG0000002708215


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006897  Hepatocyte nuclear factor 1, beta isoform, C-terminal
 IPR006899  Hepatocyte nuclear factor 1, N-terminal
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR023219  Hepatocyte nuclear factor 1, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle non-contractile , abnormal
Show

 ZFA:0000017 endoderm endoderm morphology , abnormal
Show

 ZFA:0000029 hindbrain hindbrain irregular spatial pattern , abnormal
hindbrain morphology , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle circular , abnormal
otic vesicle wholly anterioralized , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000059 postoptic commissure postoptic commissure defasciculated , abnormal
postoptic commissure commissural neuron axon guidance disrupted , abnormal
Show

 ZFA:0000069 rhombomere 6 rhombomere 6 morphology , abnormal
Show

 ZFA:0000076 swim bladder swim bladder agenesis , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
Show

 ZFA:0000112 gut gut morphology , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
liver agenesis , abnormal
liver decreased size , abnormal
liver aplastic , abnormal
liver decreased distribution , abnormal
Show

 ZFA:0000140 pancreas pancreas decreased size , abnormal
pancreas agenesis , abnormal
pancreas hypoplastic , abnormal
pancreas aplastic , abnormal
pancreas variability of size , abnormal
Show

 ZFA:0000151 pronephros pronephros quality , abnormal
pronephros cystic , abnormal
pronephros distal region decreased object quality , abnormal
Show

 ZFA:0000217 inner ear inner ear quality , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal shape , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II decreased size , abnormal
cranial nerve II decreased thickness , abnormal
cranial nerve II defasciculated , abnormal
cranial nerve II commissural neuron axon guidance disrupted , abnormal
Show

 ZFA:0000529 kidney kidney cystic , abnormal
Show

 ZFA:0000823 rhombomere 5 rhombomere 5 morphology , abnormal
rhombomere 5 aplastic , abnormal
Show

 ZFA:0001076 intestinal bulb intestinal bulb structure , abnormal
Show

 ZFA:0001108 anterior commissure anterior commissure defasciculated , abnormal
anterior commissure commissural neuron axon guidance disrupted , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001210 presumptive rhombomere 6 presumptive rhombomere 6 decreased distribution , abnormal
Show

 ZFA:0001211 presumptive rhombomere 5 presumptive rhombomere 5 mislocalised , abnormal
presumptive rhombomere 5 decreased distribution , abnormal
Show

 ZFA:0001260 endocrine pancreas endocrine pancreas quality , abnormal
endocrine pancreas decreased distribution , abnormal
endocrine pancreas absent , abnormal
Show

 ZFA:0001390 pancreatic bud pancreatic bud aplastic , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0001557 pronephric glomerulus pronephric glomerulus increased distribution , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule absent , abnormal
pronephric tubule physical object quality , abnormal
Show

 ZFA:0001617 otolith otolith shape , abnormal
Show

 ZFA:0005070 atrioventricular node atrioventricular node closed , abnormal
atrioventricular node decreased functionality , abnormal
Show

 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct decreased length , abnormal
intrahepatic bile duct hypoplastic , abnormal
intrahepatic bile duct dilated , abnormal
Show

 ZFA:0005737 intestinal rod intestinal rod anterior region decreased distribution , abnormal
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 ZFA:0005738 intestinal bulb primordium intestinal bulb primordium posterior region mislocalised , abnormal
intestinal bulb primordium increased distribution , abnormal
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 ZFA:0005755 islet islet disorganized , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell decreased amount , abnormal
pancreatic B cell disorganized , abnormal
pancreatic B cell decreased area , abnormal
pancreatic B cell regeneration decreased rate , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte undifferentiated , abnormal
Show

 ZFA:0009366 hair cell hair cell mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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