ENSDARG00000022295


Danio rerio

Features
Gene ID: ENSDARG00000022295
  
Biological name :hnf1bb
  
Synonyms : hnf1bb / HNF1 homeobox Bb / Q8UW00
  
Possible biological names infered from orthology : Hepatocyte nuclear factor 1-beta / HNF1B / HNF1 homeobox B / P27889 / P35680
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 38817785
Gene end: 38840667
  
Corresponding Affymetrix probe sets: Dr.15418.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000125092
Ensembl peptide - ENSDARP00000143259
NCBI entrez gene - 324283     See in Manteia.
swissprot - F8W5H7
swissprot - Q8UW00
ZFIN ID - ZDB-GENE-030131-3003
Ensembl - ENSDARG00000022295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HNF1BENSGALG00000005504Gallus gallus
 HNF1BENSG00000275410Homo sapiens
 Hnf1bENSMUSG00000020679Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hnf1ba / HNF1 homeobox Ba / HNF1B* / P35680* / P27889* / HNF1 homeobox B* / Hepatocyte nuclear factor 1-beta *ENSDARG0000000661567
hnf1a / HNF1 homeobox aENSDARG0000000947042
CABZ01078261.1 / HMBOX1* / Q6NT76* / homeobox containing 1*ENSDARG0000010928716
zgc:91944ENSDARG0000003588716
hmbox1a / homeobox containing 1a / HMBOX1* / Q6NT76* / Q8BJA3* / homeobox containing 1* / Mus musculus homeobox containing 1 (Hmbox1), transcript variant 3, mRNA.*ENSDARG0000002708214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006897  Hepatocyte nuclear factor 1, beta isoform, C-terminal
 IPR006899  Hepatocyte nuclear factor 1, N-terminal
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR023219  Hepatocyte nuclear factor 1, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0034672 anterior/posterior pattern specification involved in pronephros development IGI
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000151 pronephros pronephros lacks all parts of type pronephric podocyte , abnormal
pronephros has extra parts of type pronephric podocyte , abnormal
pronephros poorly differentiated , abnormal
pronephros proximal region decreased object quality , abnormal
pronephros distal region decreased object quality , abnormal
Show

 ZFA:0001620 pronephric proximal convoluted tubule pronephric proximal convoluted tubule decreased diameter , abnormal
pronephric proximal convoluted tubule epithelial cell malformed , abnormal
Show

 ZFA:0001622 pronephric distal early tubule pronephric distal early tubule poorly differentiated , abnormal
Show

 ZFA:0001673 pronephric podocyte pronephric podocyte separated from pronephric podocyte , abnormal
pronephric podocyte mislocalised posteriorly , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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