ENSGALG00000005504


Gallus gallus

Features
Gene ID: ENSGALG00000005504
  
Biological name :HNF1B
  
Synonyms : HNF1B / HNF1 homeobox B
  
Possible biological names infered from orthology : Hepatocyte nuclear factor 1-beta / P27889 / P35680
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 8668217
Gene end: 8683224
  
Corresponding Affymetrix probe sets: GgaAffx.21637.1.S1_s_at (Chicken Array)   GgaAffx.3454.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008820
Ensembl peptide - ENSGALP00000051981
NCBI entrez gene - 427838     See in Manteia.
RefSeq - XM_003642414
RefSeq - XM_003642413
swissprot - E1C4J3
swissprot - A0A1D5PGQ8
Ensembl - ENSGALG00000005504
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnf1baENSDARG00000006615Danio rerio
 hnf1bbENSDARG00000022295Danio rerio
 HNF1BENSG00000275410Homo sapiens
 Hnf1bENSMUSG00000020679Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HNF1A / HNF1 homeobox A / P20823* / P22361* / Hepatocyte nuclear factor 1-alpha *ENSGALG0000000696851
HMBOX1 / homeobox-containing protein 1 / Q6NT76* / Q8BJA3* / homeobox containing 1* / Mus musculus homeobox containing 1 (Hmbox1), transcript variant 3, mRNA.*ENSGALG0000001663313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006897  Hepatocyte nuclear factor 1, beta isoform, C-terminal
 IPR006899  Hepatocyte nuclear factor 1, N-terminal
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR023219  Hepatocyte nuclear factor 1, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001714 endodermal cell fate specification IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001826 inner cell mass cell differentiation IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007492 endoderm development IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0035565 regulation of pronephros size IEA
 biological_processGO:0039020 pronephric nephron tubule development IEA
 biological_processGO:0042663 regulation of endodermal cell fate specification IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048557 embryonic digestive tract morphogenesis IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IEA
 biological_processGO:0048793 pronephros development IEA
 biological_processGO:0050673 epithelial cell proliferation IEA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0060429 epithelium development IEA
 biological_processGO:0060677 ureteric bud elongation IEA
 biological_processGO:0060993 kidney morphogenesis IEA
 biological_processGO:0061017 hepatoblast differentiation IEA
 biological_processGO:0061296 negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis IEA
 biological_processGO:0072095 regulation of branch elongation involved in ureteric bud branching IEA
 biological_processGO:0072164 mesonephric tubule development IEA
 biological_processGO:0072176 nephric duct development IEA
 biological_processGO:0072177 mesonephric duct development IEA
 biological_processGO:0072179 nephric duct formation IEA
 biological_processGO:0072181 mesonephric duct formation IEA
 biological_processGO:1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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