ENSDARG00000007231


Danio rerio

Features
Gene ID: ENSDARG00000007231
  
Biological name :ryk
  
Synonyms : receptor-like tyrosine kinase / ryk
  
Possible biological names infered from orthology : Q01887 / Tyrosine-protein kinase RYK
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 27514465
Gene end: 27615701
  
Corresponding Affymetrix probe sets: Dr.3476.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073853
Ensembl peptide - ENSDARP00000106622
NCBI entrez gene - 558502     See in Manteia.
RefSeq - NM_001083826
RefSeq - XM_005165931
RefSeq Peptide - NP_001077295
swissprot - E7FAI5
swissprot - A2RRV7
ZFIN ID - ZDB-GENE-070209-277
Ensembl - ENSDARG00000007231
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RYKENSGALG00000006488Gallus gallus
 RYKENSG00000163785Homo sapiens
 RykENSMUSG00000032547Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mertka / c-mer proto-oncogene tyrosine kinase a / MERTK* / Q12866* / Q60805* / Tyrosine-protein kinase Mer * / MER proto-oncogene, tyrosine kinase*ENSDARG0000007469524
tyro3 / TYRO3 protein tyrosine kinase / P55144* / Q06418* / TYRO3 protein tyrosine kinase 3*ENSDARG0000000535624
mst1rb / macrophage stimulating 1 receptor b / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000000487124
met / MET proto-oncogene, receptor tyrosine kinase / P08581*ENSDARG0000007090324
mst1ra / macrophage stimulating 1 receptor a / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000006023524
tie1 / tyrosine kinase with immunoglobulin-like and EGF-like domains 1 / P35590* / Q06806*ENSDARG0000000410522
si:ch73-40a2.1ENSDARG0000010552120
tek / TEK tyrosine kinase, endothelial / Q02763* / TEK receptor tyrosine kinase*ENSDARG0000002866320
AXL / AXL receptor tyrosine kinase / P30530*ENSDARG0000011204520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003306  WIF domain
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007223 Wnt signaling pathway, calcium modulating pathway IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IMP
 biological_processGO:0060026 convergent extension IGI
 biological_processGO:0060028 convergent extension involved in axis elongation IMP
 biological_processGO:0060030 dorsal convergence IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain rhombomere condensed , abnormal
Show

 ZFA:0000155 somite somite condensed , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001115 trunk trunk decreased length , abnormal
trunk somite increased width , abnormal
Show

 ZFA:0001329 retinal inner plexiform layer retinal inner plexiform layer disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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