ENSG00000163785


Homo sapiens

Features
Gene ID: ENSG00000163785
  
Biological name :RYK
  
Synonyms : receptor-like tyrosine kinase / RYK
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.2
Gene start: 134065303
Gene end: 134250744
  
Corresponding Affymetrix probe sets: 202853_s_at (Human Genome U133 Plus 2.0 Array)   214172_x_at (Human Genome U133 Plus 2.0 Array)   216976_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419122
Ensembl peptide - ENSP00000487023
Ensembl peptide - ENSP00000485095
Ensembl peptide - ENSP00000478721
Ensembl peptide - ENSP00000417836
NCBI entrez gene - 6259     See in Manteia.
OMIM - 600524
RefSeq - NM_001005861
RefSeq - NM_002958
RefSeq Peptide - NP_001005861
RefSeq Peptide - NP_002949
swissprot - A0A0D9SFZ4
swissprot - H7C4P6
swissprot - A0A096LNL3
swissprot - A0A087WUK1
swissprot - H0Y8A4
Ensembl - ENSG00000163785
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rykENSDARG00000007231Danio rerio
 RYKENSGALG00000006488Gallus gallus
 RykENSMUSG00000032547Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TYRO3 / Q06418 / TYRO3 protein tyrosine kinaseENSG0000009244529
MERTK / Q12866 / MER proto-oncogene, tyrosine kinaseENSG0000015320827
MST1R / Q04912 / macrophage stimulating 1 receptorENSG0000016407827
AXL / P30530 / AXL receptor tyrosine kinaseENSG0000016760126
MET / P08581 / MET proto-oncogene, receptor tyrosine kinaseENSG0000010597626
TIE1 / P35590 / tyrosine kinase with immunoglobulin like and EGF like domains 1ENSG0000006605622
TEK / Q02763 / TEK receptor tyrosine kinaseENSG0000012015621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003306  WIF domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr