ENSDARG00000005356


Danio rerio

Features
Gene ID: ENSDARG00000005356
  
Biological name :tyro3
  
Synonyms : tyro3 / TYRO3 protein tyrosine kinase
  
Possible biological names infered from orthology : P55144 / Q06418 / TYRO3 protein tyrosine kinase 3
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 10501647
Gene end: 10553538
  
Corresponding Affymetrix probe sets: Dr.8144.1.S1_at (Zebrafish Array)   NM_131432_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000116623
NCBI entrez gene - 30709     See in Manteia.
RefSeq - NM_131432
RefSeq Peptide - NP_571507
swissprot - B3DGN7
ZFIN ID - ZDB-GENE-990714-13
Ensembl - ENSDARG00000005356
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TYRO3ENSGALG00000008631Gallus gallus
 TYRO3ENSG00000092445Homo sapiens
 Tyro3ENSMUSG00000027298Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mertka / c-mer proto-oncogene tyrosine kinase a / MERTK* / Q12866* / Q60805* / Tyrosine-protein kinase Mer * / MER proto-oncogene, tyrosine kinase*ENSDARG0000007469537
AXL / AXL receptor tyrosine kinase / P30530*ENSDARG0000011204535
si:ch73-40a2.1ENSDARG0000010552124
mst1rb / macrophage stimulating 1 receptor b / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000000487122
tie1 / tyrosine kinase with immunoglobulin-like and EGF-like domains 1 / P35590* / Q06806*ENSDARG0000000410521
tek / TEK tyrosine kinase, endothelial / Q02763* / TEK receptor tyrosine kinase*ENSDARG0000002866321
met / MET proto-oncogene, receptor tyrosine kinase / P08581*ENSDARG0000007090321
mst1ra / macrophage stimulating 1 receptor a / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000006023521
ryk / receptor-like tyrosine kinase / Q01887* / Tyrosine-protein kinase RYK *ENSDARG0000000723116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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