ENSGALG00000008631


Gallus gallus

Features
Gene ID: ENSGALG00000008631
  
Biological name :TYRO3
  
Synonyms : TYRO3 / tyrosine-protein kinase receptor TYRO3 precursor
  
Possible biological names infered from orthology : P55144 / Q06418 / TYRO3 protein tyrosine kinase / TYRO3 protein tyrosine kinase 3
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 24921251
Gene end: 24960510
  
Corresponding Affymetrix probe sets: Gga.4266.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014051
NCBI entrez gene - 395336     See in Manteia.
RefSeq - NM_204627
RefSeq Peptide - NP_989958
swissprot - F1NLR2
Ensembl - ENSGALG00000008631
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tyro3ENSDARG00000005356Danio rerio
 TYRO3ENSG00000092445Homo sapiens
 Tyro3ENSMUSG00000027298Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MERTK / tyrosine-protein kinase Mer precursor / Q12866* / Q60805* / Tyrosine-protein kinase Mer * / MER proto-oncogene, tyrosine kinase*ENSGALG0000000825738
MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*ENSGALG0000003688322
MST1R / macrophage-stimulating protein receptor precursor / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSGALG0000000310322
TEK / TEK receptor tyrosine kinase / Q02763* / Q02858*ENSGALG0000000184021
TIE1 / tyrosine kinase with immunoglobulin like and EGF like domains 1 / P35590* / Q06806*ENSGALG0000000995720
RYK / receptor-like tyrosine kinase / Q01887* / Tyrosine-protein kinase RYK *ENSGALG0000000648817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001779 natural killer cell differentiation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021885 forebrain cell migration IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0034122 negative regulation of toll-like receptor signaling pathway IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0042698 ovulation cycle IEA
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045824 negative regulation of innate immune response IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0051250 negative regulation of lymphocyte activation IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0070050 neuron cellular homeostasis IEA
 biological_processGO:0070527 platelet aggregation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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