ENSDARG00000074695


Danio rerio

Features
Gene ID: ENSDARG00000074695
  
Biological name :mertka
  
Synonyms : c-mer proto-oncogene tyrosine kinase a / mertka
  
Possible biological names infered from orthology : MER proto-oncogene, tyrosine kinase / MERTK / Q12866 / Q60805 / Tyrosine-protein kinase Mer
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 47623916
Gene end: 47691710
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101815
Ensembl peptide - ENSDARP00000113911
NCBI entrez gene - 100322133     See in Manteia.
swissprot - B8JME4
swissprot - F1QWE3
ZFIN ID - ZDB-GENE-081107-1
Ensembl - ENSDARG00000074695
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MERTKENSGALG00000008257Gallus gallus
 MERTKENSG00000153208Homo sapiens
 MertkENSMUSG00000014361Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tyro3 / TYRO3 protein tyrosine kinase / P55144* / Q06418* / TYRO3 protein tyrosine kinase 3*ENSDARG0000000535634
AXL / AXL receptor tyrosine kinase / P30530*ENSDARG0000011204531
si:ch73-40a2.1ENSDARG0000010552121
met / MET proto-oncogene, receptor tyrosine kinase / P08581*ENSDARG0000007090321
mst1rb / macrophage stimulating 1 receptor b / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000000487120
mst1ra / macrophage stimulating 1 receptor a / MST1R* / Q04912* / Q62190* / macrophage stimulating 1 receptor* / macrophage stimulating 1 receptor (c-met-related tyrosine kinase)*ENSDARG0000006023520
tek / TEK tyrosine kinase, endothelial / Q02763* / TEK receptor tyrosine kinase*ENSDARG0000002866318
tie1 / tyrosine kinase with immunoglobulin-like and EGF-like domains 1 / P35590* / Q06806*ENSDARG0000000410518
ryk / receptor-like tyrosine kinase / Q01887* / Tyrosine-protein kinase RYK *ENSDARG0000000723115


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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