ENSDARG00000007257


Danio rerio

Features
Gene ID: ENSDARG00000007257
  
Biological name :rab5ab
  
Synonyms : rab5ab / RAB5A, member RAS oncogene family, b
  
Possible biological names infered from orthology : AC099811.2 / Q9CQD1 / Rab5a / Ras-related protein Rab-5A
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 49647402
Gene end: 49661406
  
Corresponding Affymetrix probe sets: Dr.14542.1.S1_at (Zebrafish Array)   NM_200970_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000123595
Ensembl peptide - ENSDARP00000010427
NCBI entrez gene - 393945     See in Manteia.
RefSeq - NM_200970
RefSeq Peptide - NP_957264
swissprot - E9QBQ1
swissprot - Q7ZUG4
ZFIN ID - ZDB-GENE-040122-3
Ensembl - ENSDARG00000007257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB5AENSGALG00000011272Gallus gallus
 AC099811.2ENSG00000267261Homo sapiens
 Rab5aENSMUSG00000017831Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rab5aa / RAB5A, member RAS oncogene family, a / Rab5a* / Q9CQD1* / AC099811.2* / Ras-related protein Rab-5A *ENSDARG0000001860294
rab5c / RAB5C, member RAS oncogene family / P35278* / P51148*ENSDARG0000002671284
rab5b / RAB5B, member RAS oncogene familyENSDARG0000001605970
rab22a / RAB22A, member RAS oncogene family / P35285* / Q9UL26*ENSDARG0000001580744
LO018490.1 / RAB31* / Q13636* / RAB31, member RAS oncogene family*ENSDARG0000011583242
RAB21 / zgc:154045 / P35282* / Q9UL25* / RAB21, member RAS oncogene family*ENSDARG0000010075239
rab20 / RAB20, member RAS oncogene family / P35295* / Q9NX57* / Ras-related protein Rab-20 *ENSDARG0000000504934
Q6IMK3 / dnajc27 / DnaJ (Hsp40) homolog, subfamily C, member 27 / Q8CFP6* / Q9NZQ0* / DnaJ homolog subfamily C member 27 * / DnaJ heat shock protein family (Hsp40) member C27*ENSDARG0000007091625


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0038092 nodal signaling pathway IMP
 biological_processGO:0051489 regulation of filopodium assembly IBA
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0060061 Spemann organizer formation IMP
 cellular_componentGO:0005769 early endosome IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0030139 endocytic vesicle IBA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000071 shield shield absent , abnormal
Show

 ZFA:0000086 EVL EVL secondary lysosome increased amount , abnormal
EVL cell morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001176 blastoderm blastoderm morphology , abnormal
blastoderm separated from yolk , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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