ENSDARG00000007959


Danio rerio

Features
Gene ID: ENSDARG00000007959
  
Biological name :hibadhb
  
Synonyms : 3-hydroxyisobutyrate dehydrogenase b / hibadhb
  
Possible biological names infered from orthology : 3-hydroxyisobutyrate dehydrogenase / HIBADH / P31937 / Q99L13
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 20871015
Gene end: 20889516
  
Corresponding Affymetrix probe sets: Dr.14021.2.S1_at (Zebrafish Array)   Dr.14021.3.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000003030
swissprot - F1QE62
ZFIN ID - ZDB-GENE-040426-1582
Ensembl - ENSDARG00000007959
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HIBADHENSGALG00000033207Gallus gallus
 HIBADHENSG00000106049Homo sapiens
 HibadhENSMUSG00000029776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hibadha / 3-hydroxyisobutyrate dehydrogenase a / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*ENSDARG0000010290682
glyr1 / glyoxylate reductase 1 homolog (Arabidopsis) / Q49A26* / Q922P9* / glyoxylate reductase 1 homolog* / Putative oxidoreductase GLYR1 *ENSDARG0000009921321
BX601646.1 / GLYR1* / Q49A26* / glyoxylate reductase 1 homolog*ENSDARG0000011658814


Protein motifs (from Interpro)
Interpro ID Name
 IPR002204  3-hydroxyisobutyrate dehydrogenase-related, conserved site
 IPR006115  6-phosphogluconate dehydrogenase, NADP-binding
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR011548  3-hydroxyisobutyrate dehydrogenase
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR015815  3-hydroxyisobutyrate dehydrogenase-related
 IPR016040  NAD(P)-binding domain
 IPR029154  3-hydroxyisobutyrate dehydrogenase, NAD-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006574 valine catabolic process IEA
 biological_processGO:0009083 branched-chain amino acid catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEA
 molecular_functionGO:0008442 3-hydroxyisobutyrate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007959 hibadhb / 3-hydroxyisobutyrate dehydrogenase b / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*  / complex
 ENSDARG00000102906 hibadha / 3-hydroxyisobutyrate dehydrogenase a / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*  / complex






 

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