ENSDARG00000102906


Danio rerio

Features
Gene ID: ENSDARG00000102906
  
Biological name :hibadha
  
Synonyms : 3-hydroxyisobutyrate dehydrogenase a / hibadha
  
Possible biological names infered from orthology : 3-hydroxyisobutyrate dehydrogenase / HIBADH / P31937 / Q99L13
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 19599528
Gene end: 19657539
  
Corresponding Affymetrix probe sets: Dr.5994.1.A1_at (Zebrafish Array)   Dr.5994.2.S1_at (Zebrafish Array)   NM_001003646_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130898
Ensembl peptide - ENSDARP00000152893
Ensembl peptide - ENSDARP00000141727
Ensembl peptide - ENSDARP00000137289
NCBI entrez gene - 445252     See in Manteia.
RefSeq - NM_001003646
RefSeq Peptide - NP_001003646
swissprot - A0A0R4IZ21
swissprot - A0A0R4IA23
swissprot - A0A0J9YJE8
ZFIN ID - ZDB-GENE-040801-264
Ensembl - ENSDARG00000102906
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HIBADHENSGALG00000033207Gallus gallus
 HIBADHENSG00000106049Homo sapiens
 HibadhENSMUSG00000029776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hibadhb / 3-hydroxyisobutyrate dehydrogenase b / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*ENSDARG0000000795982
glyr1 / glyoxylate reductase 1 homolog (Arabidopsis) / Q49A26* / Q922P9* / glyoxylate reductase 1 homolog* / Putative oxidoreductase GLYR1 *ENSDARG0000009921323
BX601646.1 / GLYR1* / Q49A26* / glyoxylate reductase 1 homolog*ENSDARG0000011658816


Protein motifs (from Interpro)
Interpro ID Name
 IPR002204  3-hydroxyisobutyrate dehydrogenase-related, conserved site
 IPR006115  6-phosphogluconate dehydrogenase, NADP-binding
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR011548  3-hydroxyisobutyrate dehydrogenase
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR015815  3-hydroxyisobutyrate dehydrogenase-related
 IPR016040  NAD(P)-binding domain
 IPR029154  3-hydroxyisobutyrate dehydrogenase, NAD-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006574 valine catabolic process IEA
 biological_processGO:0009083 branched-chain amino acid catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEA
 molecular_functionGO:0008442 3-hydroxyisobutyrate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007959 hibadhb / 3-hydroxyisobutyrate dehydrogenase b / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*  / complex
 ENSDARG00000102906 hibadha / 3-hydroxyisobutyrate dehydrogenase a / HIBADH* / Q99L13* / P31937* / 3-hydroxyisobutyrate dehydrogenase*  / complex






 

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