ENSGALG00000033207


Gallus gallus

Features
Gene ID: ENSGALG00000033207
  
Biological name :HIBADH
  
Synonyms : 3-hydroxyisobutyrate dehydrogenase / HIBADH
  
Possible biological names infered from orthology : P31937 / Q99L13
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 32894746
Gene end: 32976993
  
Corresponding Affymetrix probe sets: GgaAffx.11848.1.S1_s_at (Chicken Array)   GgaAffx.7036.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052157
Ensembl peptide - ENSGALP00000057750
Ensembl peptide - ENSGALP00000055058
Ensembl peptide - ENSGALP00000054076
NCBI entrez gene - 420632     See in Manteia.
RefSeq - NM_001006362
RefSeq Peptide - NP_001006362
swissprot - A0A1D5PQ96
swissprot - A0A1D5PMJ7
swissprot - A0A1D5PH80
swissprot - Q5ZLI9
Ensembl - ENSGALG00000033207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hibadhaENSDARG00000102906Danio rerio
 hibadhbENSDARG00000007959Danio rerio
 HIBADHENSG00000106049Homo sapiens
 HibadhENSMUSG00000029776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GLYR1 / putative oxidoreductase GLYR1 / Q49A26* / Q922P9* / glyoxylate reductase 1 homolog*ENSGALG0000003833826


Protein motifs (from Interpro)
Interpro ID Name
 IPR002204  3-hydroxyisobutyrate dehydrogenase-related, conserved site
 IPR006115  6-phosphogluconate dehydrogenase, NADP-binding
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR011548  3-hydroxyisobutyrate dehydrogenase
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR015815  3-hydroxyisobutyrate dehydrogenase-related
 IPR016040  NAD(P)-binding domain
 IPR029154  3-hydroxyisobutyrate dehydrogenase, NAD-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006574 valine catabolic process IEA
 biological_processGO:0009083 branched-chain amino acid catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEA
 molecular_functionGO:0008442 3-hydroxyisobutyrate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000033207 HIBADH / 3-hydroxyisobutyrate dehydrogenase / P31937* / Q99L13*  / complex






 

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contact: otassy@igbmc.fr