ENSDARG00000008835


Danio rerio

Features
Gene ID: ENSDARG00000008835
  
Biological name :A2ML1 (1 of many)
  
Synonyms : A2ML1 (1 of many) / si:dkey-46g23.5
  
Possible biological names infered from orthology : A2ML1 / A8K2U0 / alpha-2-macroglobulin like 1
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 3432960
Gene end: 3448095
  
Corresponding Affymetrix probe sets: Dr.4412.13.A1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073345
Ensembl peptide - ENSDARP00000008576
NCBI entrez gene - 562067     See in Manteia.
RefSeq - NM_001201405
RefSeq Peptide - NP_001188334
swissprot - F1R2I8
swissprot - F1QS86
ZFIN ID - ZDB-GENE-030131-9306
Ensembl - ENSDARG00000008835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000000293Gallus gallus
 ENSGALG00000014252Gallus gallus
 A2ML1ENSGALG00000036447Gallus gallus
 A2ML1ENSG00000166535Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:171446 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011600585
si:dkey-46g23.2 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011581785
zgc:171445 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011520584
zgc:165518 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000007573780
zgc:165453 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000007818378
sb:cb37 / si:dkey-105h12.2 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000004164556
si:ch211-212c13.10 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000009319956
a2ml / alpha-2-macroglobulin-like / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000005631456
si:dkey-105h12.2 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000004168555
zgc:171426 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000007476445
A2ML1 (1 of many) / si:ch211-212c13.8 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000007875744
cpamd8 / C3 and PZP-like, alpha-2-macroglobulin domain containing 8 / Q8IZJ3*ENSDARG0000005653025
cd109 / CD109 molecule / Q6YHK3* / Q8R422* / CD109 antigen *ENSDARG0000006060923
c4 / complement component 4 / C4A* / C4B* / P0C0L5* / P01029* / P0C0L4* / complement C4B (Chido blood group)* / complement C4A (Rodgers blood group)* / Complement C4-B Complement C4 beta ch...ENSDARG0000001506520
c3a.3 / complement component c3a, duplicate 3 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000005220720
c3a.1 / complement component c3a, duplicate 1 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000001269420
c3a.2 / complement component c3a, duplicate 2 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000008735920
c3a.4 / complement component c3a, duplicate 4 / C3* / P01024* / complement C3*ENSDARG0000009319820
si:dkey-8k3.2ENSDARG0000003842420
c3a.6 / complement component c3a, duplicate 6 / C3* / P01024* / complement C3*ENSDARG0000004371919


Protein motifs (from Interpro)
Interpro ID Name
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR009048  Alpha-macroglobulin, receptor-binding
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming
 IPR019742  Alpha-2-macroglobulin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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