ENSGALG00000036447


Gallus gallus

Features
Gene ID: ENSGALG00000036447
  
Biological name :A2ML1
  
Synonyms : A2ML1 / alpha-2-macroglobulin like 1
  
Possible biological names infered from orthology : A8K2U0
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 76082957
Gene end: 76112683
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000047023
NCBI entrez gene - 418254     See in Manteia.
RefSeq - XM_015292744
RefSeq - XM_015292764
RefSeq - XM_015292749
RefSeq - XM_015292757
swissprot - A0A1D5P2X2
Ensembl - ENSGALG00000036447
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 a2mlENSDARG00000056314Danio rerio
 A2ML1 (1 of many)ENSDARG00000078757Danio rerio
 sb:cb37ENSDARG00000041645Danio rerio
 si:ch211-212c13.10ENSDARG00000093199Danio rerio
 si:dkey-105h12.2ENSDARG00000041685Danio rerio
 si:dkey-46g23.2ENSDARG00000115817Danio rerio
 si:dkey-46g23.5ENSDARG00000008835Danio rerio
 zgc:165453ENSDARG00000078183Danio rerio
 zgc:165518ENSDARG00000075737Danio rerio
 zgc:171426ENSDARG00000074764Danio rerio
 zgc:171445ENSDARG00000115205Danio rerio
 zgc:171446ENSDARG00000116005Danio rerio
 A2ML1ENSG00000166535Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000029339
PZP* / A2M* / Mug2* / Mug1* / Q6GQT1* / Gm7298* / P01023* / P20742* / P28665* / P28666* / Q61838* / Murinoglobulin-2 * / Murinoglobulin-1 * / alpha-2-macroglobulin* / PZP, alpha-2-macroglob...ENSGALG0000003976435
OVST / ovostatin precursor / A2ml1* / Q3UU35* / alpha-2-macroglobulin like 1*ENSGALG0000001193035
ENSGALG0000001425233
CD109 / CD109 molecule / Q6YHK3* / Q8R422* / CD109 antigen *ENSGALG0000001591025
PZP* / A2M* / Mug2* / Mug1* / Q6GQT1* / Gm7298* / P01023* / P20742* / P28665* / P28666* / Q61838* / Murinoglobulin-2 * / Murinoglobulin-1 * / alpha-2-macroglobulin* / PZP, alpha-2-macroglob...ENSGALG0000003165925
ENSGALG0000001704020
CPAMD8 / C3 and PZP like, alpha-2-macroglobulin domain containing 8 / Q8IZJ3*ENSGALG0000000374220
C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*ENSGALG0000000156519
C4 / complement 4 precursor / C4A* / C4B* / P0C0L5* / P01029* / P0C0L4* / complement C4B (Chido blood group)* / complement C4A (Rodgers blood group)* / Complement C4-B Complement C4 beta c...ENSGALG0000003223118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR007990  Prolactin-inducible protein
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR009048  Alpha-macroglobulin, receptor-binding
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR014756  Immunoglobulin E-set
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming
 IPR019742  Alpha-2-macroglobulin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0052548 regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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