ENSGALG00000039764


Gallus gallus

Features
Gene ID: ENSGALG00000039764
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : A2M / alpha-2-macroglobulin / Gm7298 / Mug1 / Mug2 / Murinoglobulin-1 / Murinoglobulin-2 / P01023 / P20742 / P28665 / P28666 / Pregnancy zone protein Alpha-2-macroglobulin 165 kDa subunit Alpha-2-macroglobulin 35 kDa subunit / PZP / PZP, alpha-2-macroglobulin like / Q61838 / Q6GQT1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 76230134
Gene end: 76257737
  
Corresponding Affymetrix probe sets: Gga.1714.1.S1_at (Chicken Array)   GgaAffx.9042.4.S1_at (Chicken Array)   GgaAffx.9045.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050420
NCBI entrez gene - 418251     See in Manteia.
RefSeq - XM_015292681
swissprot - A0A1D5PCD2
Ensembl - ENSGALG00000039764
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A2MENSG00000175899Homo sapiens
 PZPENSG00000126838Homo sapiens
 A2mENSMUSG00000030111Mus musculus
 Gm7298ENSMUSG00000108022Mus musculus
 Mug1ENSMUSG00000059908Mus musculus
 Mug2ENSMUSG00000030131Mus musculus
 PzpENSMUSG00000030359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PZP* / A2M* / Mug2* / Mug1* / Q6GQT1* / Gm7298* / P01023* / P20742* / P28665* / P28666* / Q61838* / Murinoglobulin-2 * / Murinoglobulin-1 * / alpha-2-macroglobulin* / PZP, alpha-2-macroglob...ENSGALG0000003165951
OVST / ovostatin precursor / A2ml1* / Q3UU35* / alpha-2-macroglobulin like 1*ENSGALG0000001193042
ENSGALG0000000029339
A2ML1 / alpha-2-macroglobulin like 1 / A8K2U0*ENSGALG0000003644736
ENSGALG0000001425233
CD109 / CD109 molecule / Q6YHK3* / Q8R422* / CD109 antigen *ENSGALG0000001591027
CPAMD8 / C3 and PZP like, alpha-2-macroglobulin domain containing 8 / Q8IZJ3*ENSGALG0000000374221
ENSGALG0000001704020
C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*ENSGALG0000000156519
C4 / complement 4 precursor / C4A* / C4B* / P0C0L5* / P01029* / P0C0L4* / complement C4B (Chido blood group)* / complement C4A (Rodgers blood group)* / Complement C4-B Complement C4 beta c...ENSGALG0000003223118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR003344  Big-1 (bacterial Ig-like domain 1) domain
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR009048  Alpha-macroglobulin, receptor-binding
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR014756  Immunoglobulin E-set
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming
 IPR019742  Alpha-2-macroglobulin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Degradation of the extracellular matrix
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr