ENSGALG00000031659


Gallus gallus

Features
Gene ID: ENSGALG00000031659
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : A2M / alpha-2-macroglobulin / Gm7298 / Mug1 / Mug2 / Murinoglobulin-1 / Murinoglobulin-2 / P01023 / P20742 / P28665 / P28666 / Pregnancy zone protein Alpha-2-macroglobulin 165 kDa subunit Alpha-2-macroglobulin 35 kDa subunit / PZP / PZP, alpha-2-macroglobulin like / Q61838 / Q6GQT1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 76270315
Gene end: 76327369
  
Corresponding Affymetrix probe sets: GgaAffx.7577.1.S1_at (Chicken Array)   GgaAffx.9042.5.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050315
Ensembl peptide - ENSGALP00000055938
Ensembl peptide - ENSGALP00000057102
swissprot - A0A1D5PSQ1
swissprot - A0A1D5PVX4
Ensembl - ENSGALG00000031659
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A2MENSG00000175899Homo sapiens
 PZPENSG00000126838Homo sapiens
 A2mENSMUSG00000030111Mus musculus
 Gm7298ENSMUSG00000108022Mus musculus
 Mug1ENSMUSG00000059908Mus musculus
 Mug2ENSMUSG00000030131Mus musculus
 PzpENSMUSG00000030359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PZP* / A2M* / Mug2* / Mug1* / Q6GQT1* / Gm7298* / P01023* / P20742* / P28665* / P28666* / Q61838* / Murinoglobulin-2 * / Murinoglobulin-1 * / alpha-2-macroglobulin* / PZP, alpha-2-macroglob...ENSGALG0000003976465
OVST / ovostatin precursor / A2ml1* / Q3UU35* / alpha-2-macroglobulin like 1*ENSGALG0000001193038
ENSGALG0000000029333
A2ML1 / alpha-2-macroglobulin like 1 / A8K2U0*ENSGALG0000003644733
ENSGALG0000001425230
CD109 / CD109 molecule / Q6YHK3* / Q8R422* / CD109 antigen *ENSGALG0000001591024
CPAMD8 / C3 and PZP like, alpha-2-macroglobulin domain containing 8 / Q8IZJ3*ENSGALG0000000374223
ENSGALG0000001704018
C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*ENSGALG0000000156517
C4 / complement 4 precursor / C4A* / C4B* / P0C0L5* / P01029* / P0C0L4* / complement C4B (Chido blood group)* / complement C4A (Rodgers blood group)* / Complement C4-B Complement C4 beta c...ENSGALG0000003223117


Protein motifs (from Interpro)
Interpro ID Name
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR014756  Immunoglobulin E-set
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming
 IPR019742  Alpha-2-macroglobulin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Degradation of the extracellular matrix
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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