ENSDARG00000010276


Danio rerio

Features
Gene ID: ENSDARG00000010276
  
Biological name :ptgs2b
  
Synonyms : prostaglandin-endoperoxide synthase 2b / ptgs2b
  
Possible biological names infered from orthology : P35354 / prostaglandin-endoperoxide synthase 2 / Prostaglandin G/H synthase 2 / PTGS2 / Q05769
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 34121818
Gene end: 34127415
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000003684
NCBI entrez gene - 559020     See in Manteia.
RefSeq - NM_001025504
RefSeq Peptide - NP_001020675
swissprot - Q5RI06
ZFIN ID - ZDB-GENE-041014-323
Ensembl - ENSDARG00000010276
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGS2ENSGALG00000033635Gallus gallus
 PTGS2ENSG00000073756Homo sapiens
 Ptgs2ENSMUSG00000032487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptgs2a / prostaglandin-endoperoxide synthase 2a / PTGS2* / Q05769* / P35354* / Prostaglandin G/H synthase 2 * / prostaglandin-endoperoxide synthase 2*ENSDARG0000000453971
ptgs1 / prostaglandin-endoperoxide synthase 1 / P22437* / P23219*ENSDARG0000005214861


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR010255  Haem peroxidase
 IPR019791  Haem peroxidase, animal type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0019371 cyclooxygenase pathway IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IDA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 molecular_functionGO:0004601 peroxidase activity IDA
 molecular_functionGO:0004666 prostaglandin-endoperoxide synthase activity IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging
Synthesis of 15-eicosatetraenoic acid derivatives
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Biosynthesis of DHA-derived SPMs
Biosynthesis of EPA-derived SPMs
Biosynthesis of DPAn-3 SPMs
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010276 ptgs2b / prostaglandin-endoperoxide synthase 2b / PTGS2* / Q05769* / P35354* / Prostaglandin G/H synthase 2 * / prostaglandin-endoperoxide synthase 2*  / complex






 

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