ENSDARG00000011373


Danio rerio

Features
Gene ID: ENSDARG00000011373
  
Biological name :mknk2a
  
Synonyms : MAP kinase interacting serine/threonine kinase 2a / mknk2a
  
Possible biological names infered from orthology : MAP kinase interacting serine/threonine kinase 2 / MAP kinase-interacting serine/threonine-protein kinase 2 / MKNK2 / Q8CDB0 / Q9HBH9
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 23006792
Gene end: 23024952
  
Corresponding Affymetrix probe sets: Dr.6680.1.S1_at (Zebrafish Array)   NM_212723_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000008879
Ensembl peptide - ENSDARP00000131031
NCBI entrez gene - 334167     See in Manteia.
RefSeq - NM_212723
RefSeq Peptide - NP_997888
swissprot - B0S8G7
swissprot - A0A0R4ICK3
ZFIN ID - ZDB-GENE-030131-6099
Ensembl - ENSDARG00000011373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MKNK2ENSGALG00000003845Gallus gallus
 MKNK2ENSG00000099875Homo sapiens
 Mknk2ENSMUSG00000020190Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mknk2b / MAP kinase interacting serine/threonine kinase 2b / MKNK2* / Q8CDB0* / Q9HBH9* / MAP kinase interacting serine/threonine kinase 2* / MAP kinase-interacting serine/threonine-protein...ENSDARG0000001516483
mknk1 / MAP kinase interacting serine/threonine kinase 1 / Q9BUB5*ENSDARG0000001841156
mapkapk2b / mitogen-activated protein kinase-activated protein kinase 2b / P49138* / P49137* / MAPKAPK2* / MAP kinase-activated protein kinase 2 * / mitogen-activated protein kinase-activat...ENSDARG0000001853025
mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*ENSDARG0000002808224
mapkapk2a / mitogen-activated protein kinase-activated protein kinase 2a / P49138* / P49137* / MAPKAPK2* / MAP kinase-activated protein kinase 2 * / mitogen-activated protein kinase-activat...ENSDARG0000000255224
mapkapk3 / mitogen-activated protein kinase-activated protein kinase 3 / Q16644*ENSDARG0000011161224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0046777 protein autophosphorylation IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0009931 calcium-dependent protein serine/threonine kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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