ENSGALG00000003845


Gallus gallus

Features
Gene ID: ENSGALG00000003845
  
Biological name :MKNK2
  
Synonyms : MAP kinase interacting serine/threonine kinase 2 / MKNK2
  
Possible biological names infered from orthology : MAP kinase-interacting serine/threonine-protein kinase 2 / Q8CDB0 / Q9HBH9
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2131519
Gene end: 2137639
  
Corresponding Affymetrix probe sets: GgaAffx.2393.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006100
NCBI entrez gene - 429269     See in Manteia.
RefSeq - XM_015299873
swissprot - F1NCK3
Ensembl - ENSGALG00000003845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mknk2aENSDARG00000011373Danio rerio
 mknk2bENSDARG00000015164Danio rerio
 MKNK2ENSG00000099875Homo sapiens
 Mknk2ENSMUSG00000020190Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MKNK1 / MAP kinase interacting serine/threonine kinase 1 / Q9BUB5*ENSGALG0000001044064
MAPKAPK3 / Gallus gallus mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3), mRNA. / Q16644* / Q3UMW7* / MAP kinase-activated protein kinase 3 * / mitogen-activated prot...ENSGALG0000000228326
MAPKAPK2 / mitogen-activated protein kinase-activated protein kinase 2 / P49137* / P49138* / MAP kinase-activated protein kinase 2 *ENSGALG0000000088325
MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41* / O54992* / Gm42878* / MAP kinase-activated protein kinase 5 *ENSGALG0000000474325


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046777 protein autophosphorylation IBA
 biological_processGO:0071243 cellular response to arsenic-containing substance IEA
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004683 calmodulin-dependent protein kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0009931 calcium-dependent protein serine/threonine kinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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