ENSDARG00000111612


Danio rerio

Features
Gene ID: ENSDARG00000111612
  
Biological name :mapkapk3
  
Synonyms : mapkapk3 / mitogen-activated protein kinase-activated protein kinase 3
  
Possible biological names infered from orthology : MAP kinase-activated protein kinase 3 / Q16644 / Q3UMW7
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 34580085
Gene end: 34628789
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000157636
swissprot - A0A0R4IU49
ZFIN ID - ZDB-GENE-061215-124
Ensembl - ENSDARG00000111612
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPKAPK3ENSGALG00000002283Gallus gallus
 Q16644ENSG00000114738Homo sapiens
 Q3UMW7ENSMUSG00000032577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapkapk2a / mitogen-activated protein kinase-activated protein kinase 2a / P49138* / P49137* / MAPKAPK2* / MAP kinase-activated protein kinase 2 * / mitogen-activated protein kinase-activat...ENSDARG0000000255266
mapkapk2b / mitogen-activated protein kinase-activated protein kinase 2b / P49138* / P49137* / MAPKAPK2* / MAP kinase-activated protein kinase 2 * / mitogen-activated protein kinase-activat...ENSDARG0000001853061
mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*ENSDARG0000002808237
mknk2b / MAP kinase interacting serine/threonine kinase 2b / MKNK2* / Q8CDB0* / Q9HBH9* / MAP kinase interacting serine/threonine kinase 2* / MAP kinase-interacting serine/threonine-protein...ENSDARG0000001516429
mknk1 / MAP kinase interacting serine/threonine kinase 1 / Q9BUB5*ENSDARG0000001841128
mknk2a / MAP kinase interacting serine/threonine kinase 2a / MKNK2* / Q8CDB0* / Q9HBH9* / MAP kinase interacting serine/threonine kinase 2* / MAP kinase-interacting serine/threonine-protein...ENSDARG0000001137328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR027442  MAP kinase activated protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
p38MAPK events
Oxidative Stress Induced Senescence
VEGFA-VEGFR2 Pathway
activated TAK1 mediates p38 MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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