ENSDARG00000013434


Danio rerio

Features
Gene ID: ENSDARG00000013434
  
Biological name :hira
  
Synonyms : hira / histone cell cycle regulator a
  
Possible biological names infered from orthology : histone cell cycle regulator / P54198 / Protein HIRA / Q61666
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 18047111
Gene end: 18072844
  
Corresponding Affymetrix probe sets: Dr.4473.1.A1_at (Zebrafish Array)   XM_691386_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000119160
NCBI entrez gene - 568076     See in Manteia.
RefSeq - XM_691386
swissprot - A2CEX6
ZFIN ID - ZDB-GENE-030131-6296
Ensembl - ENSDARG00000013434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HIRAENSGALG00000033598Gallus gallus
 HIRAENSG00000100084Homo sapiens
 HiraENSMUSG00000022702Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011494  TUP1-like enhancer of split
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019015  HIRA B motif
 IPR019775  WD40 repeat, conserved site
 IPR031120  WD repeat HIR1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006336 DNA replication-independent nucleosome assembly IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0031935 regulation of chromatin silencing IBA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0031491 nucleosome binding IBA


Pathways (from Reactome)
Pathway description
Formation of Senescence-Associated Heterochromatin Foci (SAHF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000069912 hmga2 / high mobility group AT-hook 2 / P52926* / P52927*  / reaction / complex
 ENSDARG00000038559 h1f0 / H1 histone family, member 0 / P07305* / P10922* / Histone H1.0 Histone H1.0, N-terminally processed*  / reaction
 ENSDARG00000078781 si:ch211-161c3.6 / HMGA2* / P52926* / P52927* / high mobility group AT-hook 2*  / reaction / complex






 

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