ENSDARG00000015325


Danio rerio

Features
Gene ID: ENSDARG00000015325
  
Biological name :u2af1
  
Synonyms : u2af1 / U2 small nuclear RNA auxiliary factor 1
  
Possible biological names infered from orthology : P0DN76 / Q01081 / Q9D883 / U2AF1L5 / U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 / U2 small nuclear RNA auxiliary factor 1 like 5
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 9230446
Gene end: 9242777
  
Corresponding Affymetrix probe sets: Dr.18312.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000005582
swissprot - F1RB94
ZFIN ID - ZDB-GENE-020419-1
Ensembl - ENSDARG00000015325
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 U2AF1ENSGALG00000016198Gallus gallus
 P0DN76ENSG00000275895Homo sapiens
 U2AF1ENSG00000160201Homo sapiens
 U2af1ENSMUSG00000061613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zrsr2 / zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 / Zrsr1* / Q15696* / Q64707* / zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1*ENSDARG0000005844832


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR000571  Zinc finger, CCCH-type
 IPR003954  RNA recognition motif domain, eukaryote
 IPR009145  U2 auxiliary factor small subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0089701 U2AF IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary condensed , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000737 cranium cranium hypoplastic , abnormal
cranium malformed , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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