ENSG00000160201


Homo sapiens

Features
Gene ID: ENSG00000160201
  
Biological name :U2AF1
  
Synonyms : Q01081 / U2AF1 / U2 small nuclear RNA auxiliary factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.3
Gene start: 43092956
Gene end: 43107587
  
Corresponding Affymetrix probe sets: 202858_at (Human Genome U133 Plus 2.0 Array)   231904_at (Human Genome U133 Plus 2.0 Array)   232141_at (Human Genome U133 Plus 2.0 Array)   234731_at (Human Genome U133 Plus 2.0 Array)   242499_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420672
Ensembl peptide - ENSP00000418705
Ensembl peptide - ENSP00000489632
Ensembl peptide - ENSP00000291552
Ensembl peptide - ENSP00000369629
Ensembl peptide - ENSP00000381205
NCBI entrez gene - 7307     See in Manteia.
OMIM - 191317
RefSeq - XM_017028468
RefSeq - NM_001025203
RefSeq - NM_001025204
RefSeq - NM_006758
RefSeq - XM_011529743
RefSeq Peptide - NP_001020375
RefSeq Peptide - NP_006749
RefSeq Peptide - NP_001020374
swissprot - Q01081
swissprot - A0A1B0GW87
Ensembl - ENSG00000160201
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 u2af1ENSDARG00000015325Danio rerio
 U2AF1ENSGALG00000016198Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P0DN76 / U2AF1L5 / U2 small nuclear RNA auxiliary factor 1 like 5ENSG00000275895100
Q8WU68 / U2AF1L4 / U2 small nuclear RNA auxiliary factor 1 like 4ENSG0000016126542
ZRSR2 / Q15696 / zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2ENSG0000016924934
AD000671.2ENSG0000026712023


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR000571  Zinc finger, CCCH-type
 IPR003954  RNA recognition motif domain, eukaryote
 IPR009145  U2 auxiliary factor small subunit
 IPR035979  RNA-binding domain superfamily
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0015030 Cajal body TAS
 cellular_componentGO:0016607 nuclear speck ISS
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 cellular_componentGO:0089701 U2AF IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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