ENSG00000161265


Homo sapiens

Features
Gene ID: ENSG00000161265
  
Biological name :U2AF1L4
  
Synonyms : Q8WU68 / U2AF1L4 / U2 small nuclear RNA auxiliary factor 1 like 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.12
Gene start: 35742464
Gene end: 35745445
  
Corresponding Affymetrix probe sets: 226700_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473940
Ensembl peptide - ENSP00000475046
Ensembl peptide - ENSP00000474493
Ensembl peptide - ENSP00000292879
Ensembl peptide - ENSP00000368258
Ensembl peptide - ENSP00000397645
Ensembl peptide - ENSP00000465170
Ensembl peptide - ENSP00000465242
Ensembl peptide - ENSP00000467441
Ensembl peptide - ENSP00000469891
Ensembl peptide - ENSP00000471804
NCBI entrez gene - 199746     See in Manteia.
OMIM - 601080
RefSeq - NM_001040425
RefSeq - NM_144987
RefSeq Peptide - NP_659424
RefSeq Peptide - NP_001035515
swissprot - Q8WU68
swissprot - S4R353
swissprot - S4R3L8
swissprot - A0A1D5RMU4
swissprot - S4R443
swissprot - K7EJH3
swissprot - K7EJM7
swissprot - M0QYK5
swissprot - M0R1E1
Ensembl - ENSG00000161265
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8BGJ9ENSMUSG00000109378Mus musculus
 Q8BGJ9ENSMUSG00000078765Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
U2AF1 / Q01081 / U2 small nuclear RNA auxiliary factor 1ENSG0000016020150
P0DN76 / U2AF1L5 / U2 small nuclear RNA auxiliary factor 1 like 5ENSG0000027589550
ZRSR2 / Q15696 / zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2ENSG0000016924929
AD000671.2ENSG0000026712025


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR000571  Zinc finger, CCCH-type
 IPR003954  RNA recognition motif domain, eukaryote
 IPR009145  U2 auxiliary factor small subunit
 IPR035979  RNA-binding domain superfamily
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0089701 U2AF IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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